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CC BY-NC-ND 4.0 · Sleep Sci 2017; 10(04): 161-167
DOI: 10.5935/1984-0063.20170028
REVIEW ARTICLE

Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy with Centrotemporal Spikes: A Systematic Review and Meta-analysis

Camila dos Santos Halal
1   Pontificia Universidade Católica do Rio Grande do Sul (PUCRS), PhD Program of Medicine and Health Sciences - Porto Alegre - Rio Grande do Sul - Brazil
2   Conceição Hospital Group, Hospital Criança Conceição - Porto Alegre - Rio Grande do Sul - Brazil
,
Bernardo Lessa Horta
3   Universidade Federal de Pelotas, Postgraduate Program in Epidemiology, Pelotas, Rio Grande do Sul, Brazil
,
Magda Lahorgue Nunes
4   Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine and Brain Institute (BRAIns), Division of Neurology, Porto Alebre, Rio Grande do Sul, Brazil
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Self-limited epilepsy with centrotemporal spikes is the most common paediatric epileptic syndrome, with growing evidence linking it to various degrees and presentations of neuropsychological dysfunction. The objective of this study is to evaluate the possible sleep macro and microstructural alterations in children with this diagnosis. A systematic review of published manuscripts was carried out in Medline, LILACS and Scielo databases, using the MeSH terms epilepsy, sleep and polysomnography. From 753 retrieved references, 5 were selected, and data from macro and, when available, microstructure of sleep were extracted. Meta-analysis was performed with data from 4 studies using standardized mean difference. Findings were heterogeneous between studies, being the most frequent macrostructural findings a smaller proportion and greater latency of REM sleep in two studies and, in meta-analysis, a longer sleep latency was the most significant finding among epileptic patients. Only one study evaluated sleep microstructure, suggesting possible alterations in cyclic alternating pattern in diagnosed children. Studies evaluating macro and microstructure of sleep in children with self-limited epilepsy with centrotemporal spikes are necessary to a better understanding of mechanisms of the neuropsychologic disturbances that are frequently seen in children with this diagnosis.

Sleep - Epilepsy - Polysomnography


Publication History

Received: 17 July 2017

Accepted: 20 September 2017

Article published online:
11 October 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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