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CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(03): 301-305
DOI: 10.4103/wjnm.WJNM_86_19
Case Report

18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures

Apichaya Claimon
Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
,
Ngoentra Tantranont
1   Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
,
Torpong Claimon
2   Department of Radiology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand
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Abstract

Adrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%—10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. Detection of hyperfunctional bilateral adrenocortical carcinoma by 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F- FDG PET/CT) has never been reported. Herein, we report a male patient who presented with Cushing's syndrome, type II diabetes mellitus due to Cushing's syndrome, and hypogonadism with biopsy confirmed left ACC. He underwent 18F-FDG PET/CT to evaluate the contralateral adrenal mass and to plan for laparoscopic adrenalectomy, which subsequently confirmed bilateral ACC. Furthermore,18F-FDG PET/CT was useful in staging, which revealed paraaortic lymph node and lung metastasis.

Keywords

18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography - adrenal cortical carcinoma - bilateral - Cushing's syndrome - laparoscopic adrenalectomy

Financial support and sponsorship

The research authors (Apichaya Claimon and Ngoentra Tantranont) received a Chalermphrakiat grant from the Faculty of Medicine, Siriraj Hospital, Mahidol University.




Publication History

Received: 27 November 2019

Accepted: 10 February 2020

Article published online:
19 April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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