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CC BY-NC-ND 4.0 · World J Nucl Med 2019; 18(04): 428-430
DOI: 10.4103/wjnm.WJNM_64_18
Case Report

Positron emission tomography-computed tomography in subcutaneous panniculitis-like T-cell lymphoma

Prathyusha Bikkina
Department of Nuclear Medicine and PET-CT, Basavatarakam Indo American Cancer Hospital, Hyderabad, Telangana, India
,
Kamala Reddy
1   Department of Radiology, Basavatarakam Indo American Cancer Hospital, Hyderabad, Telangana, India
,
Zakir Ali
Department of Nuclear Medicine and PET-CT, Basavatarakam Indo American Cancer Hospital, Hyderabad, Telangana, India
,
Naveen Kumar
Department of Nuclear Medicine and PET-CT, Basavatarakam Indo American Cancer Hospital, Hyderabad, Telangana, India
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Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare and poorly differentiated type of cutaneous T-cell lymphoma. In this variant, the lymphoma cells infiltrate preferentially into the subcutaneous adipose tissue. It is an indolent type of non-Hodgkin's lymphoma and can be mistaken for panniculitis. Here, we describe the case of a 59-year-old female patient who presented with altered skin pigmentation with diffuse plaque-like patches in the skin around the thighs and legs. A skin biopsy revealed subcutaneous lobular panniculitis composed of lymphocytes, epithelioid histiocytes, and occasional giant cells admixed with atypical lymphoid cells, which were suggestive of cutaneous lymphoma. Immunohistochemistry showed CD3 positive, CD20 negative, CD8 positive, CD4 occasional cells positive, CD56 negative, and CD5 few cells positive, confirming the diagnosis of SPTCL. Therefore, cases with atypical and nonresolving dermatological lesions should raise a suspicion of SPTCL as diagnosis against other benign conditions.

Keywords

Fluorodeoxyglucose positron emission tomography-computed tomography - non-Hodgkin's lymphoma - subcutaneous panniculitis-like T-cell lymphoma

Financial support and sponsorship

Nil.




Publication History

Received: 04 July 2018

Accepted: 27 July 2018

Article published online:
22 April 2022

© 2019. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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