Open Access
CC BY-NC-ND 4.0 · South Asian J Cancer 2017; 06(04): 179-185
DOI: 10.4103/sajc.sajc_209_17
Letter to the Editor

Good response to erlotinib in a patient after progression on osimertinib: A rare case of spatiotemporal T790M heterogeneity in a patient with epidermal growth factor receptor-mutant nonsmall cell lung cancer

Authors

  • Venkata Pradeep Babu Koyyala

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Ullas Batra

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Parveen Jain

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Mansi Sharma

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Pankaj Goyal

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Kshitiz Domadia

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
  • Sneha Botra

    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India

Source of Support: Nill.
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Publication History

Article published online:
22 December 2020

© 2017. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Hata A, Katakami N, Yoshioka H, Kaji R, Masago K, Fujita S, et al. Spatiotemporal T790M heterogeneity in individual patients with EGFR-mutant non-small-cell lung cancer after acquired resistance to EGFR-TKI. J Thorac Oncol 2015;10:1553-9.
  • 2 Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 2008;359:366-77.
  • 3 Su KY, Chen HY, Li KC, Kuo ML, Yang JC, Chan WK, et al. Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer. J Clin Oncol 2012;30:433-40.