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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2017; 27(02): 129-132
DOI: 10.4103/ijri.IJRI_341_16
Neuroradiology

Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy

Rupinder Singh
Department of Neuroradiology, Sri Bala Ji Action Medical Institute, New Delhi, India
,
Ramanjeet Kaur
Department of Gynaecology, Kasturba Hospital, New Delhi, India
,
Pawan Pokhariyal
Department of Neurology, Sri Bala Ji Action Medical Institute, New Delhi, India
,
Rajul Aggarwal
Department of Neurology, Sri Bala Ji Action Medical Institute, New Delhi, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such cases which presented initially with splenial hyperintesity and showed progression to characterstic lesions. Both cases improved with stoppage of metronidazole.

Keywords

Magnetic resonance imaging - metronidazole - metronidazole-induced encephalopathy - splenial hyperintensity


Publication History

Article published online:
27 July 2021

© 2017. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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