CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(02): 116-120
DOI: 10.4103/ijmpo.ijmpo_95_20
Review Article

Novel Coronavirus Infection – Knowns and Unknowns with Particular Reference to Oncology – Combating against COVID-19 with “COVID”

Janice Tsang
Specialist in Medical Oncology, Hon. Clinical Assistant Professor, Hong Kong Breast Oncology Group, Li Ka Shing Faculty of Medicine, The University of Hong Kong, China
,
Jyoti Bajpai
Department of Medical Oncology, Tata Memorial Centre, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

We are facing yet another global pandemic with the novel coronavirus (COVID-19) outbreak and anticipate that second and even third wave of the infection may come if we do not practise constant vigilance! An advent of a mysterious outbreak of atypical pneumonia in December 2019, traced from the seafood wholesale market in Wuhan of China, spread the wings over the world in very short span. Like both severe acute respiratory syndrome coronavirus (CoV) and MERS-CoV infections, the risk of severe disease increases substantially with age and with the presence of underlying conditions. While cancer is a prevalent disease and a global health challenge, little information is available with regard to the implications of COVID-19 for cancer patients. So far, the data have been limited and fragmented. COVID-19 with different primary cancer types will have different biological behaviours with highly variable disease courses and diverse treatment strategies. Any generalized conclusions for all cancer patients with respect to COVID-19 should be interpreted with caution until we have sufficient prospective data. Enormous work needs to be done to study the specific unmet needs of cancer patients with the challenge of the COVID-19; the prevention still is the best remedy. Infection control measures should be enforced continuously, and public health education and engagement should be highly recommended. We propose to join hands together to combat against COVID-19 with some simple tips for our cancer patients to raise their awareness of this public health challenge – combating against COVID-19 with “COVID:” Continue “social distancing;” Omit unnecessary face-to-face meting or meal gathering or mass event, make use of cyber meeting, and bring one's own lunch box to work; Visage protection, i.e. universal precaution with surgical masks when going out in a large crowd such as public transport or any close contact in high-risk area; Infection control of the hands with hand hygiene at all times and; Diet, lifestyle, and exercise continue to be balanced and healthy.



Publication History

Received: 16 March 2020

Accepted: 19 March 2020

Article published online:
23 May 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 World Health Organization. Available from https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen
  • 2 Su S, Wong G, Shi W, Liu J, Lai ACK, Zhou J. et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses. Trends Microbiol 2016; 24: 490-502
  • 3 Fan Y, Zhao K, Shi ZL, Zhou P. Bat coronaviruses in China. Viruses 2019; 11: E210
  • 4 Wuhan Municipal Health Commission. Update on Outbreak of Pneumonia Cases in Wuhan, Chinese; 31 Dec 2019. http://wjw.wuhan.gov.cn/front/web/showDetail/2019123108989 Available from: [Last accessed on 2020 Jan 13]
  • 5 Wuhan Municipal Health Commission. Report on unexplained viral pneumonia. Chinese: 11 January 2020. http://wjw.wuhan.gov.cn/front/web/showDetail/2020011109035 Available from: [Last accessed on 2020 Jan 21]
  • 6 Cheung J. Ill Husband and Wife Add to Wuhan Riddle. Hong Kong: The Standard; 2020. httos://www.thestandard.com.hk/sections-news-print/215457/ill-husban-and-wife—add-to-Wuhan-riddle Available from: [Last accessed on 2020 Jan 20]
  • 7 Wu P, Hao X, Lau EHY, Wong JY, Leung KSM, Wu JT. et al. Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020. Euro Surveill. 2020 Jan 25(3). DOI: 10.2807/1560-7917.ES.2020.25.3.2000044.
  • 8 Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020; 395: 514-23
  • 9 Guan WJ, Ni ZY, Liang WH, Ou CQ, He JX, Liu L. et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; DOI: 10.1056/NEJMoa2002032. Feb 28 [Epub ahead of print]
  • 10 Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506
  • 11 Centre for Health Protection. Severe Respiratory Disease Associated with a Novel Infectious Agent -Letters to Doctors; 2020. https://www.chp.giv.hk/en/miniweb/letters/100063.html Available from: [Last accessed on 2020 Feb 05]
  • 12 To KK, Tsang OT, Yip CC, Chan KH, Wu TC, Chan JM. et al. Consistent detection of 2019 novel coronavirus in saliva. Clin Infect Dis 2020; pii-ciaa149
  • 13 Cowling BJ, Muller MP, Wong IO, Ho LM, Lo SV, Tsang T. et al. Clinical prognostic rules for severe acute respiratory syndrome in low- and high-resource settings. Arch Intern Med 2006; 166: 1505-11
  • 14 Lau EH, Hsiung CA, Cowling BJ, Chen CH, Ho LM, Tsang T. et al. A comparative epidemiologic analysis of SARS in Hong Kong, Beijing and Taiwan. BMC Infect Dis 2010; 10: 50
  • 15 Hui DS, Azhar EI, Kim YJ, Memish ZA, Oh MD, Zumla A. Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission. Lancet Infect Dis 2018; 18: e217-27
  • 16 Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L. et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clin Res Cardiol 2020; DOI: 10.1007/s00392-020-01626-9. Mar 11 [Epub ahead of print]
  • 17 Liang W, Guan W, Chen R, Wang W, Li J, Xu K. et al. Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China. Lancet Oncol 2020; 21: 335-7
  • 18 Xia Y, Jin R, Zhao J, Li W, Shen H. Risk of COVID-19 for cancer patients. Lancet Oncol 2020; pii S1470-2045 (20) 30150-9. doi: 10.1016/S1470-2045 (20) 30150-9
  • 19 Yang L, Xu HY, Wang Y. Diagnostic and therapeutic strategies of lung cancer patients during the outbreak of 2019 novel coronavirus disease (COVID-19). Zhonghua Zhong Liu Za Zhi 2020; 42: E006
  • 20 Zhang H, Huang Y, Xie C. The treatment and outcome of a lung cancer patient infected with SARS-CoV-2. J Thorac Oncol 2020; pii S1556-0864 (20) 30191-X
  • 21 Yang C, Li C, Wang S. Clinical strategies for treatment pediatric cancer during the outbreak of 2019 novel coronavirus infection. Pediatr Blood Cancer 2020 2020; 2020: e28248
  • 22 Lai THT, Tang EWH, Chau SKY, Fung KSC, Li KKW. Stepping up infection control measures in ophthalmology during the novel coronavirus outbreak: an experience from Hong Kong. Graefes Arch Clin Exp Ophthalmol 2020; DOI: 10.1007/s00417-020-04641-8. Mar 3 [Epub ahead of print]
  • 23 LeBlanc TW, Kamal AH. Assessing psychological toxicity and patient-reported distress as the sixth vital sign in cancer care and clinical trials. AMA J Ethics 2017; 19: 460-6
  • 24 Liu BL, Ma F, Wang JN, Fan Y, Mo HN, Xu BH. Health management of breast caner patients outside the hospital outbreak of 2019 novel coronavirus disease. Zhonghua Zhong Liu Za Zhi 2020; 42: E002