CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(03): 415-417
DOI: 10.4103/ijmpo.ijmpo_201_18
Practitioner Section

Malignant Ossifying Fibromyxoid Tumor of the Tongue: A Rare Case

Aarti Mittal
Department of Pathology, SMS Medical College and Attached Hospital, Jaipur, Rajasthan, India
,
Swati Sharma
Department of Pathology, SMS Medical College and Attached Hospital, Jaipur, Rajasthan, India
,
Deepika Hemrajani
Department of Pathology, SMS Medical College and Attached Hospital, Jaipur, Rajasthan, India
,
Vijaya Devi
Department of Pathology, SMS Medical College and Attached Hospital, Jaipur, Rajasthan, India
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

Ossifying fibromyxoid tumors (OFMTs) are rare musculoskeletal tumors of uncertain malignant potential. Most OFMTs arise from the subcutaneous tissue, skeletal muscles of extremities, trunk, or head-and-neck region. OFMTs are usually benign, but atypical and malignant OFMT have been described with recurrence and distant metastasis. Till date, the etiopathogenesis and exact line of differentiation of OFMT is still doubtful. We are presenting an unusual case of malignant OFMT of the tongue. It is a rare case of malignant OFMT affecting an unusual site.



Publication History

Received: 12 September 2018

Accepted: 10 November 2019

Article published online:
28 June 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Enzinger FM, Weiss SW, Liang CY. Ossifying fibromyxoid tumor of soft parts. A clinicopathological analysis of 59 cases. Am J Surg Pathol 1989; 13: 817-27
  • 2 Folpe AL, Weiss SW. Ossifying fibromyxoid tumor of soft parts: A clinicopathologic study of 70 cases with emphasis on atypical and malignant variants. Am J Surg Pathol 2003; 27: 421-31
  • 3 Ohta K, Taki M, Ogawa I, Ono S, Mizuta K, Fujimoto S. et al. Malignant ossifying fibromyxoid tumor of the tongue: Case report and review of the literature. Head Face Med 2013; 9: 16
  • 4 Williams RW, Case CP, Irvine GH. Ossifying fibromyxoid tumour of soft parts--a new tumour of the parotid/zygomatic arch region. Br J Oral Maxillofac Surg 1994; 32: 174-7
  • 5 Kilpatrick SE, Ward WG, Mozes M, Miettinen M, Fukunaga M, Fletcher CD. Atypical and malignant variants of ossifying fibromyxoid tumor. Clinicopathologic analysis of six cases. Am J Surg Pathol 1995; 19: 1039-46
  • 6 Graham RP, Dry S, Li X, Binder S, Bahrami A, Raimondi SC. et al. Ossifying fibromyxoid tumor of soft parts: A clinicopathologic, proteomic, and genomic study. Am J Surg Pathol 2011; 35: 1615-25
  • 7 Donner LR. Ossifying fibromyxoid tumor of soft parts: Evidence supporting Schwann cell origin. Hum Pathol 1992; 23: 200-2
  • 8 Gebre-Medhin S, Nord KH, Möller E, Mandahl N, Magnusson L, Nilsson J. et al. Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors. Am J Pathol 2012; 181: 1069-77