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DOI: 10.4103/ijmbs.ijmbs_9_20
A rare encounter in nonsuspecting circumstances: First congenital visceral leishmaniasis (kala-azar) in Libya
Congenital transmission of Leishmaniasis is very rare. It occurs through blood exchange from the mother to the child during pregnancy or delivery. We report the first confirmed congenital leishmaniasis in a 4-month-old Libyan boy with prolonged jaundice and hepatosplenomegaly. This was a congenital transmission from his mother who was asymptomatic and not known to have leishmaniasis, which was confirmed after the diagnosis of the infant. Despite treatment, the infant died. The diagnostic approach is illustrated by the case report. Poor obstetric history in the mother may be related to her own undiagnosed kala azar.
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Publikationsverlauf
Eingereicht: 01. Februar 2020
Angenommen: 26. März 2020
Artikel online veröffentlicht:
07. Juli 2022
© 2020. The Libyan Authority of Scientific Research and Technologyand the Libyan Biotechnology Research Center. All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License,permitting copying and reproductionso long as the original work is given appropriate credit. Contents may not be used for commercial purposes, oradapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Karimi A, Alborzi A, Amanati A. Visceral leishmaniasis: An update and literature review. Arch Pediatr Infect Dis 2016;4:e31612.
- 2 Dabirzadeh M, Hashemi M, Maroufi Y. Study of genetic variation of leishmania major based on internal transcribe spacer 1 (ITS1) in Chabahar, Iran. Jundishapur J Microbiol 2016;9:e33498.
- 3 Alencar JE, Neves J, Dietze R. Leishmaniose visceral (calazar). In: Veronesi R, Focaccia R, Dietze R, editors. Tratado De Infectologia. 9th ed. Tratado de Infectologia. Sa˜o Paulo: Atheneu; 1997.
- 4 Annajar B. Collaborative Research Opportunities in North Africa and the Middle East Conference. Research Abstract; 22-25 June, 2009.
- 5 Elhosk MA, Shaibi T, Annajar BB, Scalini A, Maroli M. A preliminary investigation on Phlebotomus Longicusps Nitzulescu the suscpected vector of visceral leishmaniasis in the North Easthern region of Libya. Int J Adv Res 2014;2:411.
- 6 Meinecke CK, Schottelius J, Oskam L, Fleischer B. Congenital transmission of visceral leishmaniasis (Kala Azar) from an asymptomatic mother to her child. Pediatrics 1999;104:e65.
- 7 Boehme CC, Hain U, Novosel A, Eichenlaub S, Fleischmann E, Löscher T. Congenital visceral leishmaniasis. Emerg Infect Dis 2006;12:359-60.
- 8 Sundar S, Chakravarty J. An update on pharmacotherapy for leishmaniasis. Expert Opin Pharmacother 2015;16:237-52.
- 9 Figueiro-Filho EA, Duarte G, El-Beitune P, Quintana SM, Maia TL. Visceral leishmaniasis (kala-azar) and pregnancy. Infect Dis Obstet Gynecol 2004;12:31-40.
- 10 Panagopoulos P, Mitsopoulos V, Papadopoulos A, Theodorou S, Christodoulaki C, Aloupogiannis K, et al. Visceral leishmaniasis during pregnancy: A rare case report from Greece. PLoS Negl Trop Dis 2017;11:e0005134.
- 11 Sangraula H, Sharma KK, Rijal S, Dwivedi S, Koirala S. Orally effective drugs for kala-azar (visceral leishmaniasis): Focus on miltefosine and sitamaquine. J Assoc Physicians India 2003;51:686-90.