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CC BY-NC-ND 4.0 · Asian J Neurosurg 2021; 16(03): 618-622
DOI: 10.4103/ajns.AJNS_525_20
Case Report

Extra-axial desmoplastic medulloblastoma in adult cerebellopontine angle: Case report and noninvasive molecular subgrouping utilizing magnetic resonance imaging-based radiomics nomogram

Sundus Ali
Department of Neurosurgery, Mayo Hospital, King Edward Medical University, Lahore
,
Adnan Qasim
Department of Neurosurgery, Mayo Hospital, King Edward Medical University, Lahore
,
Shahzaib Tasdique
Department of Neurosurgery, Mayo Hospital, King Edward Medical University, Lahore
,
Muhammad Sarwar
Department of Neurosurgery, Mayo Hospital, King Edward Medical University, Lahore
,
Shahzad Shams
Department of Neurosurgery, Mayo Hospital, King Edward Medical University, Lahore
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Cerebellopontine angle (CPA) is an atypical site for adult medulloblastoma (MB) with only 12 cases reported in pure extra-axial location. None was predicted on preoperative imaging while the most common misdiagnosis was petrous meningioma. We add the 13th case to this list, attempting to reiterate the radiological features for preoperative prediction of this rare pathology on conventional magnetic resonance imaging (MRI). Molecular subtyping also is not yet reported for adult extra-axial CPA MB. We propose the routine use of MRI-based nomograms, in atypical CPA extra-axial masses, for noninvasive prediction of molecular subgroup, especially in resource-limited setups that lack the facility of genetic profiling.

Key-words:

Adult - cerebellopontine angle - medulloblastoma - radiomics

Financial support and sponsorship

Nil.




Publication History

Received: 04 December 2020

Accepted: 20 March 2021

Article published online:
16 August 2022

© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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