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CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(03): 1037-1039
DOI: 10.4103/ajns.AJNS_32_17
Case Report

Acute hydrocephalus caused by cerebellar abscess in HIV-negative castleman's disease

Angelo Rusconi
Department of Biotechnology and Life Sciences, University of Insubria, Varese
,
Alessandro Dario
1   Neurosurgical Unit, Ospedale Di Circolo, Varese
,
Gianluca Agresta
Department of Biotechnology and Life Sciences, University of Insubria, Varese
,
Sergio Balbi
Department of Biotechnology and Life Sciences, University of Insubria, Varese
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Castleman's disease (CD) is a rare and indolent hematologic disorder characterized by solitary bulky adenopathy. Multiple nodal nonbulky localizations are described, while central nervous system involvement is rare. Immunodeficiency is associated with higher incidence of CD, and HIV serology should be performed at initial diagnosis. We report the case of a 64-year-old HIV-negative man affected by CD, presenting with acute hydrocephalus caused by a large cerebellar abscess.

Key-words:

Castleman's disease - cerebral abscess - HIV - hydrocephalus - stereotactic brain surgery

Financial support and sponsorship

Nil.




Publication History

Article published online:
09 September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Cronin DM, Warnke RA. Castleman disease: An update on classification and the spectrum of associated lesions. Adv Anat Pathol 2009;16:236-46.
  • 2 Talat N, Belgaumkar AP, Schulte KM. Surgery in castleman's disease: A systematic review of 404 published cases. Ann Surg 2012;255:677-84.
  • 3 Talat N, Schulte KM. Castleman's disease: Systematic analysis of 416 patients from the literature. Oncologist 2011;16:1316-24.
  • 4 Zhu SH, Yu YH, Zhang Y, Sun JJ, Han DL, Li J, et al. Clinical features and outcome of patients with HIV-negative multicentric castleman's disease treated with combination chemotherapy: A report on 10 patients. Med Oncol 2013;30:492.
  • 5 Coca S, Salas I, Martínez R, Saez MA, Vaquero J. Meningeal castleman's disease with multifocal involvement: A case report and review of literature. J Neurooncol 2008;88:37-41.
  • 6 Brouwer MC, Tunkel AR, McKhann GM 2nd, van de Beek D. Brain abscess. N Engl J Med 2014;371:447-56.
  • 7 Ko SJ, Park KJ, Park DH, Kang SH, Park JY, Chung YG, et al. Risk factors associated with poor outcomes in patients with brain abscesses. J Korean Neurosurg Soc 2014;56:34-41.
  • 8 Arima T, Natsume A, Hatano H, Nakahara N, Fujita M, Ishii D, et al. Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. Case report. J Neurosurg 2005;102:733-7.
  • 9 Matsumura K, Nakasu S, Tanaka T, Nioka H, Matsuda M. Intracranial localized castleman's disease. Case report. Neurol Med Chir (Tokyo) 2005;45:59-65.