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CC BY-NC-ND 4.0 · J Lab Physicians 2019; 11(01): 091-093
DOI: 10.4103/JLP.JLP_119_18
Case Report

Role of immunohistochemistry in diagnosis of a rare bladder tumor

Manjari Kishore
Department of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India
,
Purnima Malhotra
Department of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India
,
Minakshi Bhardwaj
Department of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India
› Author Affiliations Financial support and sponsorship: Nil
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Abstract

Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.

Key words

Contrast-enhanced computed tomography - hematuria - immunohistochemistry - neuroendocrine malignancy - urinary bladder


Publication History

Received: 19 September 2018

Accepted: 22 November 2018

Article published online:
06 April 2020

© 2019.

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