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CC BY-NC-ND 4.0 · South Asian J Cancer 2013; 02(04): 260-264
DOI: 10.4103/2278-330X.119891
PEDIATRIC SECTION: Original Article

Chronic myeloid leukemia in children and adolescents: A single center experience from Eastern India

Lalit Raut
Institute of Hematology and Transfusion Medicine, Medical College and Hospital, Kolkata, West Bengal, India
,
Vinay V. Bohara
Institute of Hematology and Transfusion Medicine, Medical College and Hospital, Kolkata, West Bengal, India
,
Siddhartha S. Ray
Institute of Hematology and Transfusion Medicine, Medical College and Hospital, Kolkata, West Bengal, India
,
Prantar Chakrabarti
Institute of Hematology and Transfusion Medicine, Medical College and Hospital, Kolkata, West Bengal, India
,
Utpal Chaudhuri
Institute of Hematology and Transfusion Medicine, Medical College and Hospital, Kolkata, West Bengal, India
› Institutsangaben Source of Support: Nill.
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Abstract

Context: Chronic Myeloid Leukemia (CML) constitutes around 3% of leukemia in the children and adolescent age group. Aims: The aim of the study was to evaluate the characteristics at presentation and the treatment outcome of CML in the children and adolescent age group. Settings and Design: Retrospective analysis was carried out at a single center in India. Materials and Methods: Thirteen patients (≤17 years) attending CML outdoor from April 2008 to August 2012 were included in the analysis. Statistical Analysis Used: The mean and median of various parameters were calculated using a Microsoft excel sheet. SPSS 16.0 version software was used to calculate OS and PFS. Results: CML-CP was the most common phase at presentation. Maximum patients belonged to the 14 - 17 year old age group. Disease was common in the male sex. Splenic discomfort and asthenia were the most common symptoms and splenomegaly was the most common sign. Conclusions: The treatment with Imatinib was effective and well-tolerated.

Key words

Children and adolescents - chronic myeloid leukemia - imatinib


Publikationsverlauf

Artikel online veröffentlicht:
31. Dezember 2020

© 2013. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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