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CC BY-NC-ND 4.0 · World J Nucl Med 2015; 14(02): 134-136
DOI: 10.4103/1450-1147.154232
Case report

A Unique Case of Diffuse Metastatic Neuroendocrine Cancer with Subcutaneous Nodules on 18-F-Fluorodeoxyglucose Positron Emission Tomography/Computer Assisted Tomography

Authors

  • Mickaila Johnston

    Department of Radiology, Nuclear Medicine Division, Naval Medical Center, San Diego, 34800 Bob Wilson dr, suite 204, San Diego, CA 92134

  • Archana Sachedina

    1   Department of Radiology, Division of Nuclear Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham Steet, Little Rock, AR 72205, USA

  • James McDonald

    1   Department of Radiology, Division of Nuclear Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham Steet, Little Rock, AR 72205, USA
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Neuroendocrine tumors (NETs) account for 8-10% of cases of carcinomas of unknown primary. Most of these cases are poorly differentiated with metastatic disease at the time of diagnosis. However, cutaneous metastatic presentation is rare. We present an interesting case of a 74-year-old woman presenting with cutaneous metastatic involvement from high grade poorly differentiated NET of unknown origin. She was referred to us with a diagnosis of lymphoma. 18-F-fluorodeoxyglucose positron emission tomography/computer assisted tomography imaging at our institution offered a differential diagnosis, including neuroendocrine cancer. Repeat skin lesion biopsy demonstrated "non-Merkel cell" carcinoma, favoring metastatic high-grade neuroendocrine carcinoma.

Keywords

18-F-fluorodeoxyglucose positron emission tomography/computer-assisted tomography - neuroendocrine tumors - subcutaneous nodule


Publication History

Article published online:
21 May 2022

© 2015. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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