Download PDF
CC BY-NC-ND 4.0 · J Lab Physicians 2011; 3(01): 012-014
DOI: 10.4103/0974-2727.78554
Original Article

Human Immunodeficiency Virus Infection Among Tuberculosis Patients in Mumbai

Sandhya S Sawant
Department of Microbiology, B.Y.L. Nair Charitable Hospital, Mumbai, India
,
Sachee R Agrawal
Department of Microbiology, B.Y.L. Nair Charitable Hospital, Mumbai, India
,
Jayanthi S Shastri
Department of Microbiology, B.Y.L. Nair Charitable Hospital, Mumbai, India
,
Medha Pawaskar
Department of Microbiology, B.Y.L. Nair Charitable Hospital, Mumbai, India
,
Pradeep Kadam
Department of Microbiology, B.Y.L. Nair Charitable Hospital, Mumbai, India
› Author Affiliations Source of Support: Nil
› Further Information
  PDF Download Permissions and Reprints

ABSTRACT

Background: Human Immunodeficiency Virus (HIV) is the most powerful risk factor for the progression of Mycobacterium tuberculosis infection to Tuberculosis (TB) disease. TB accelerates the progression of HIV infection to AIDS and shortens the survival of such patients.

Aim: To determine the seroprevalence of HIV infection among TB confirmed patients in a tertiary care center in Mumbai in view of the significance of HIV in TB. Its association with gender and age was also determined.

Materials and Methods: Blood samples were collected by venipuncture from 432 TB patients and their HIV status was determined. HIV antibody detection was carried out as per Strategy III, National AIDS Control Organisation (NACO) guidelines. Statistical analysis was carried out by applying the Chi-square test.

Results and Conclusion: Of the 432 patients screened, 9% (39) were HIV positive. The prevalence of co-infection was higher among females (9.4%) than the male (8.7%) patients and highest amongst those aged 21to40 years (13.7%). Co-infection was found to be statistically highly associated with age (p < 0.05). This high prevalence calls for routine screening of TB patients for HIV infection.

Keywords

Human immunodeficiency virus - seroprevalence - Tuberculosis


Publication History

Article published online:
29 January 2020

© 2011.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

  • REFERENCES

  • 1 Yusuph H, Lailani SB, Ahedjo A. Prevalence of HIV in TB patients in Nguru, North Eastern Nigeria. Sahel Med J 2005;8:65-7.
  • 2 van Altena R, van der Werf TS. Underdiagnosis of HIV in patients with tuberculosis. Ned Tijdchr Geneesked 2007;151:2674-9.
  • 3 Sharma SK, Mohan A, Kadhiravan T. HIV/TB coinfection: Epidemiology, diagnosis and Management. Indian J Med Res 2005;121:550-67.
  • 4 Verma S, Mahajan V. HIV-tuberculosis coinfection. Int J Pulm Med 2008;10: 1
  • 5 Science Daily. Alarming New Data shows TB/HIV Coinfection a Bigger Threat. Science Daily. 2009. Available from: http://www.sciencedaily.com/releases/2009/03/090324131600.htm [Last retrieved on 2010 Sep 20].
  • 6 Maher D, Floyd K, Ravigolione M. Strategic framework to reduce the burden of HIV/TB. (WHO/CDC/TB/2002-296). Geneva: World Health Organisation; 2002.
  • 7 National AIDS Control Organization. HIV/AIDS epidemiological surveillance and estimation report for the year 2005. Available from: http:// www.nacoonline.org/fnlapil06rprt.pdf [Last accessed on 2010 Sep 20].
  • 8 World Health Organization. Treat 3 million by 2005: Epidemiological fact sheets on HIV/AIDS and sexually transmitted infections-2004 update; India. Available from: http://www.who.int/3by5/support/EFS2004_ind.pdf [Last accessed on 2010 Sep 20].
  • 9 Bertolli J, St Louis ME, Simonds RJ, Nieburg P, Kamenga M, Brown C, et al. Estimating the timing of mother to child transmission of human immunodeficiency virus in a breast feeding population in Kinshasa, Zaire. J Infect Dis 1996; 174:722-6.
  • 10 Sharma SK, Saha PK, Dixit Y, Siddaramaiah NH, Seth P, Pande JN. HIV seropositivity among adult tuberculosis patients in Delhi. Indian J Chest Dis Allied Sci 2000;42:157-60.
  • 11 Sharma SK, Aggarwal G, Seth P, Saha PK. Increasing HIV seropositivity among adult tuberculosis patients in Delhi. Indian J Med Res 2003;11:239-42.
  • 12 Piramanayagam P, Tahir M, Sharma SK, Smith-Rohrberg D, Biswas A, Vajpayee M. Persistently high HIV seroprevalence among adult tuberculosis patients at a tertiary care centre in Delhi. Indian J Med Res 2007;125:163-7.
  • 13 Ramachandran R, Datta M, Subramani R, Baskaran G, Paramasivan CN, Swaminathan S. Seroprevalence of Human Immunodeficiency Virus (HIV) infection among tuberculosis patients in Tamil Nadu. Indian J Med Res 2003;118:147-51.
  • 14 Pennap GR, Makut MD, Gyar SD, Owuna G. Seroprevalence of HIV/AIDS in Keffi and Environs. Nig J Microb 2006;20:1141-6.