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CC BY-NC-ND 4.0 · J Lab Physicians 2016; 8(01): 041-044
DOI: 10.4103/0974-2727.176232
Original Article

An Audit of Requests for Fresh Frozen Plasma in a Tertiary Care Center in South India

Jyothi B Lingegowda
Department of Pathology, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu, India
,
Joshua Daniel Jeyakumar
Department of Immunohematology and Transfusion Medicine, MGMC&RI, Puducherry, India
,
Prakash H Muddegowda
Department of Immnuhepatology and Transfusion Medicine, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu, India
,
R Pitchai
Department of Immnuhepatology and Transfusion Medicine, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu, India
,
Niranjan Gopal
Department of Biochemistry, MGMC&RI, Puducherry, India
,
Pammy Sinha
Department of Pathology, Sri Venkateswara Medical College, Puducherry, India
› Author Affiliations Financial support and sponsorship: Nil.
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ABSTRACT

Aim: To audit the fresh frozen plasma (FFP) usage with an insight into various guidelines.

Materials and Methods: The blood bank records pertaining to FFP usage in patients admitted in our medical college hospital were retrospectively reviewed for 2 years for usage of FFP in various departments and evaluated for appropriateness of usage based on various guidelines, which included the 2013 guidelines published by the National Health and Medical Research Council and the Australasian Society for Blood Transfusion.

Results: A total of 785 units of FFPs were transfused to 207 patients during the study period. The appropriate usage was found to be 59.3%, and the usage was most appropriate in massive transfusions.

Conclusion: This study highlights the nonadherence to guidelines among clinicians which is mainly due to lack of knowledge of appropriate usage.

Key words

Appropriate - audit - fresh frozen plasma


Publication History

Article published online:
19 April 2020

© 2016.

Thieme Medical and Scientific Publishers Private Ltd.
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  • REFERENCES

  • 1 Shinagare SA, Angarkar NN, Desai SR, Naniwadekar MR. An audit of fresh frozen plasma usage and effect of fresh frozen plasma on the pre-transfusion international normalized ratio. Asian J Transfus Sci 2010;4:128-32.
  • 2 Katara AA, Agravat AH, Dhruva G, Dalsania JD, Dave RG. An audit of appropriate usage of blood products in blood bank in a Tertiary Care Hospital Rajkot. Int J Curr Res Rev 2014;6:37-40.
  • 3 Peña JR, Dzik WS. Utilization management in the blood transfusion service. Clin Chim Acta 2014;427:178-82.
  • 4 Holland LL, Brooks JP. Toward rational fresh frozen plasma transfusion: The effect of plasma transfusion on coagulation test results. Am J Clin Pathol 2006;126:133-9.
  • 5 Chaudhary R, Singh H, Verma A, Ray V. Evaluation of fresh frozen plasma usage at a Tertiary Care Hospital in North India. ANZ J Surg 2005;75:573-6.
  • 6 Iorio A, Basileo M, Marchesini E, Materazzi M, Marchesi M, Esposito A, et al. The good use of plasma. A critical analysis of five international guidelines. Blood Transfus 2008;6:18-24.
  • 7 Adams RL, Bird R. Quality use of blood products. Aust Prescr 2014;37:132-6.
  • 8 Canberra: National Health and Medical Research Council (NHMRC)/Australian Society of Blood Transfusion (ASBT). Clinical Practice Guidelines. Appropriate Use of Fresh Frozen Plasma and Cryoprecipitate; C. 2001. p. 09. Available from: http://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/cp78.pdf. [Last accessed on 2015 Jun 19].
  • 9 Schofield WN, Rubin GL, Dean MG. Appropriateness of platelet, fresh frozen plasma and cryoprecipitate transfusion in New South Wales public hospitals. Med J Aust 2003;178:117-21.
  • 10 Chng WJ, Tan MK, Kuperan P. An audit of fresh frozen plasma usage in an Acute General Hospital in Singapore. Singapore Med J 2003;44:574-8.
  • 11 Iqbal H, Bhatti FA, Salamat N, Akhtar F, Hafeez K. A clinical audit of fresh frozen plasma usage. J Rawalpindi Med Coll 2013;17:122-4.
  • 12 Chang CS, Lin YC, Wu YC, Yeh CJ, Lin YC. The effects of a computerized transfusion decision support system on physician compliance and its appropriateness for fresh frozen plasma use in a medical center. Am J Clin Pathol 2011;135:417-22.
  • 13 Agarwal N, Subramanian A, Pandey RM, Albert V, Karjee S, Arya V. An audit of fresh frozen plasma usage in a Tertiary Trauma Care Centre in North India. Indian J Hematol Blood Transfus 2014;30:328-32.
  • 14 Kakkar N, Kaur R, Dhanoa J. Improvement in fresh frozen plasma transfusion practice: Results of an outcome audit. Transfus Med 2004;14:231-5.
  • 15 Sarani B, Dunkman WJ, Dean L, Sonnad S, Rohrbach JI, Gracias VH. Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection. Crit Care Med 2008;36:1114-8.