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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2010; 31(01): 36-38
DOI: 10.4103/0971-5851.68853
CASE REPORT

Florid plasmacytosis in a case of acute myeloid leukemia: A diagnostic dilemma

Aruna Rangan
Department of Hematology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India
,
Bhavna Arora
Department of Hematology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India
,
Pooja Rangan
Department of Hematology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India
,
Tina Dadu
Department of Hematology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India
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Abstract

The association of acute myeloid leukemia (AML) with plasmacytosis is a known, although rare event. There are very few case reports documenting an increase in the number of plasma cells at the time of AML diagnosis. Here, we present the case of a 65-year-old male diagnosed as acute myelomonocytic leukemia with exuberant plasmacytosis, which posed a difficulty in diagnosis. Paracrine interleukin-6 production by leukemic blast cells is thought to contribute to this associated reactive plasma cell proliferation.

Keywords

Acute myeloid leukemia - myeloma - plasmacytosis


Publication History

Article published online:
19 November 2021

© 2010. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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