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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2014; 24(02): 121-124
DOI: 10.4103/0971-3026.134386
Chest Radiology

Persistent pulmonary interstitial emphysema in a case of Langerhans cell histiocytosis

Pooja Abbey
Department of Radio-Diagnosis, Medical College and Associated Hospitals, New Delhi, India
,
Mahender K Narula
Department of Radio-Diagnosis, Medical College and Associated Hospitals, New Delhi, India
,
Rama Anand
Department of Radio-Diagnosis, Medical College and Associated Hospitals, New Delhi, India
,
Jagdish Chandra
Department of Pediatrics, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
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Abstract

We present the case of a 10-month-old boy with multisystem Langerhans cell histiocytosis showing thin-walled lung cysts along with computed tomography (CT) evidence of persistent pulmonary interstitial emphysema (PPIE), in the absence of pneumothorax or pneumomediastinum. Follow-up CT performed after 6 months demonstrated complete resolution of interstitial emphysema.

Keywords

Langerhans cell histiocytosis - lung cysts - persistent pulmonary interstitial emphysema


Publication History

Article published online:
02 August 2021

© 2014. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Schmidt S, Eich G, Hanquinet S, Tschäppeler H, Waibel P, Gudinchet F. Extra-osseous involvement of Langerhans′ cell histiocytosis in children. Pediatr Radiol 2004;34:313-21.
  • 2 Leatherwood DL, Heitkamp DE, Emerson RE. Pulmonary Langerhans cell histiocytosis. Radiographics 2007;27:265-8.
  • 3 Willman CL, Busque L, Griffith BB, Favara BE, McClain KL, Duncan MH, et al. Langerhans′-cell histiocytosis (histiocytosis X): a clonal proliferative disease. N Engl J Med 1994;331:154-60.
  • 4 Kambouchner M, Basset F, Marchal J, Uhl JF, Hance AJ, Soler P. Three-dimensional characterization of pathologic lesions in pulmonary Langerhans cell histiocytosis. Am J Respir Crit Care Med 2002;166:1483-90.
  • 5 Vassallo R, Ryu JH, Colby TV, Hartman T, Limper AH. Pulmonary Langerhans′-cell histiocytosis. N Engl J Med 2000;342:1969-78.
  • 6 Grenier P, Valeyre D, Cluzel P, Brauner MW, Lenour S, Chastang C. Chronic diffuse interstitial lung disease: Diagnostic value of chest radiography and high-resolution CT. Radiology 1991;179:123-32.
  • 7 Koyama M, Johkoh T, Honda O, Honda O, Tsubamoto M, Kozuka T, et al. Chronic cystic lung disease: Diagnostic accuracy of high-resolution CT in 92 patients. AJR Am J Roentgenol 2003;180:827-35.
  • 8 Abbott GF, Rosado-de-Christenson ML, Franks TJ, Frazier AA, Galvin JR. Pulmonary Langerhans Cell Histiocytosis. Radiographics 2004;24:821-41.
  • 9 Moore AD, Godwin JD, Müller NL, Naidich DP, Hammar SP, Buschman DL, et al. Pulmonary histiocytosis X: Comparison of radiographic and CT findings. Radiology 1989;172:249-54.
  • 10 Jabra AA, Fishman EK, Shehata BM, Perlman EJ. Localized persistent pulmonary interstitial emphysema: CT findings with radiographic pathologic correlation. AJR Am J Roentgenol 1997;169:1381-4.
  • 11 Donnelly LF, Lucaya J, Ozelame V, Frush DP, Strouse PJ, Sumner TE, et al. CT findings and temporal course of persistent pulmonary interstitial emphysema in neonates: A multiinstitutional study. AJR Am J Roentgenol 2003;180:1129-33.
  • 12 Macklin MT, Macklin CC. Malignant interstitial emphysema of the lungs and mediastinum as an importantoccult complication in many respiratory diseases and other conditions: An interpretation of the clinical literature in the light of laboratory experiment. Medicine 1944;23:281-358.