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CC BY-NC-ND 4.0 · Indian J Plast Surg 2015; 48(02): 208-211
DOI: 10.4103/0970-0358.163065
Case Report
Association of Plastic Surgeons of India

A rare case of plexiform schwannoma of the lower lip: Treatment and management

Subha Dhua
Department of Plastic and Reconstructive Surgery, Vydehi Institute of Medical Sciences and Research Centre, Whitefield, Bengaluru, Karnataka, India
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Publication History

Publication Date:
26 August 2019 (online)

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ABSTRACT

An 18-year-old female presented with a swelling on the lower lip, which was insidious in onset and gradually progressive. The mass was completely excised under local anaesthesia. Complete histopathologic and immunohistochemical studies were conducted. The Antoni A areas were found along with typical verocay bodies composed of palisading nuclei and surrounding spaces filled with eosinophilic filaments. No necrosis was noted and there were no atypical mitotic figures. In the Antoni B region, a closely textured matrix with areas of edema, myxomatous changes, cystic degeneration and dilated vessels were noted. On the basis of the histopathologic and immunohistochemical staining with S-100 protein, a diagnosis of plexiform schwannoma was made and has been reported in this study. The post-operative view confirmed complete recovery after 6 weeks of surgery. This is a rare case with the tumour located in the lower lip, as very few cases have been reported in literature and it may be the first one reported from India.

KEY WORDS

Antoni A - S-100 protein - T1-weighted images - verocay bodies
 

  • REFERENCES

  • 1 Kun Z, Qi DY, Zhang KH. A comparison between the clinical behavior of neurilemmomas in the neck and oral and maxillofacial region. J Oral Maxillofac Surg 1993; 51: 769-71
    CrossrefPubMedGoogle Scholar
  • 2 Baderca F, Cojocaru S, Lazar E, Lazureanu C, Faur A, Lighezan R. et al. Schwannoma of the lip: Case report and review of the literature. Rom J Morphol Embryol 2008; 49: 391-8
    PubMedGoogle Scholar
  • 3 Das Gupta TK, Brasfield RD, Strong EW, Hajdu SI. Benign solitary schwannomas (neurilemomas). Cancer 1969; 24: 355-66
    CrossrefPubMedGoogle Scholar
  • 4 Cardoso CL, Tolentino Ede S, Capelozza AL, Consolaro A. Schwannoma in the lower lip mucosa: Unexpected diagnosis. Quintessence Int 2010; 41: 769-71
    PubMedGoogle Scholar
  • 5 Asaumi J, Konouchi H, Kishi K. Schwannoma of the upper lip: Ultrasound, CT, and MRI findings. J Oral Maxillofac Surg 2000; 58: 1173-5
    CrossrefPubMedGoogle Scholar
  • 6 Pahwa R, Khurana N, Uma CK. et al. Neurilemmoma of tongue. Ind J Oral Surg 1968; 26: 651-8
    Google Scholar
  • 7 Cherrick HM, Eversole LR. Benign neural sheath neoplasm of the oral cavity. Report of thirty-seven cases. Oral Surg Oral Med Oral Pathol 1971; 32: 900-9
    CrossrefPubMedGoogle Scholar
  • 8 Michida A, Ryoke K, Ishikura S, Hamada T. Multiple schwannomas of the neck, mediastinum, and parapharyngeal space: Report of case. J Oral Maxillofac Surg 1995; 53: 617-20
    CrossrefPubMedGoogle Scholar
  • 9 Triaridis C, Tsalighopoulos MG, Kouloulas A, Vartholomeos A. Posterior pharyngeal wall schwannoma (case report). J Laryngol Otol 1987; 101: 749-52
    CrossrefPubMedGoogle Scholar
  • 10 De Bree R, Westerveld GJ, Smeele LE. Submandibular approach for excision of a large schwannoma in the base of the tongue. Eur Arch Otorhinolaryngol 2000; 257: 283-6
    CrossrefPubMedGoogle Scholar