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Journal of Pediatric Neuroradiology 2013; 02(04): 333-337
DOI: 10.3233/PNR-13078
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Pediatric focally pigmented choroidal melanoma: Imaging with pathological correlation

Paolo Galluzzi
a   Unit of Neuroimaging and Neurointervention (NINT), Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy
,
Rossella Occhini
b   Section of Pathology, Department of Human Pathology and Oncology, University of Siena, Siena, Italy
,
Alfonso Cerase
a   Unit of Neuroimaging and Neurointervention (NINT), Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy
,
Paolo Toti
b   Section of Pathology, Department of Human Pathology and Oncology, University of Siena, Siena, Italy
,
Theodora Hadjistilianou
c   Unit of Ophthalmology, and Retinoblastoma Referral Center, Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy
,
Carlo Venturi
a   Unit of Neuroimaging and Neurointervention (NINT), Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy
,
Sonia De Francesco
c   Unit of Ophthalmology, and Retinoblastoma Referral Center, Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy
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Further Information

Publication History

16 June 2011

23 January 2012

Publication Date:
29 July 2015 (online)

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Abstract

We report a 9-year-old-boy with no predisposing factors who presented with left eye leukocoria from a complete retinal detachment at ophthalmoscopy. Imaging showed an intraocular dome-shaped mass of low to moderate internal reflectivity at ultrasound, low T2-weighted signal intensity, lack of T1-weighted high signal intensity, and subtle gadolinium-enhancement at magnetic resonance imaging, and lack of calcifications at computed tomography. Due to the rapid extensive intraocular growth, the affected eye was enucleated. Pathologic examination showed a choroidal melanoma with only focal pigmentation. Despite its very rare incidence in the pediatric population, choroidal melanoma should be included in the differential diagnosis of leukocoria.

Keywords

Choroidal malignant melanoma - computed tomography - focal pigmentation - magnetic resonance imaging - pediatric ocular malignancy