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J Pediatr Infect Dis 2014; 09(03): 135-137
DOI: 10.3233/JPI-140425
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Antimicrobial resistance, prescribing and efficacy in children from the European to the global scene: From ARPEC to GARPEC

S. Vergnano
a   Paediatric Infectious Diseases Research Group, St George's Univeresity of London, London, UK
,
J. Bielicki
a   Paediatric Infectious Diseases Research Group, St George's Univeresity of London, London, UK
,
R. Lundin
b   PENTA Foundation, Padova, Italy
,
M. Sharland
a   Paediatric Infectious Diseases Research Group, St George's Univeresity of London, London, UK
› Author Affiliations
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Further Information

Publication History

24 August 2014

14 October 2014

Publication Date:
28 July 2015 (online)

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Abstract

Data on antimicrobial resistance and prescribing in children are sparse in spite of the high consumption in this population. In order to bridge this gap, the Antimicrobial Resistance and Prescribing in European Children project (ARPEC), was launched in 2010. Through ARPEC data on antimicrobial prescribing were collected from over 200 hospitals and primary care sources, mostly in Europe. Antimicrobial resistance patterns for a number of sentinel pathogens were described and existing guidelines on antimicrobial prescribing assembled. Finally an education tool to improve prescribing in paediatrics was set up. The main legacy of ARPEC has been the fostering of successful collaborations between paediatricians across Europe and beyond, this has resulted into GARPEC, the global side of ARPEC, aimed not only at benchmarking antimicrobial resistance and prescribing worldwide but also at developing strategies to preserve antimicrobials in the face of increasing resistance.

Keywords

Antimicrobial resistance - paediatrics - antimicrobial prescribing - Europe