CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2019; 77(05): 352-356
DOI: 10.1590/0004-282X20190032
Article

Prevalence of multiple sclerosis in Goiânia, Goiás, Brazil

Prevalência de esclerose múltipla em Goiânia, Goiás, Brasil
1   Universidade Federal de Goiás, Faculdade de Medicina, Disciplina de Neurologia, Goiânia, GO, Brasil
,
2   Instituto de Neurologia de Goiânia, Departamento de Neurologia, Goiânia, GO, Brasil
,
3   Instituto Integrado de Neurociências, Departamento de Neurociências, Goiânia, GO, Brasil
4   Hospital das Clínicas de Goiânia, Departamento de Neurociências, Goiânia, GO, Brasil
5   Hospital Geral de Goiânia, Residência Médica de Neurologia, Ambulatório de Doenças Desmielinizantes, Goiânia, GO, Brasil
,
5   Hospital Geral de Goiânia, Residência Médica de Neurologia, Ambulatório de Doenças Desmielinizantes, Goiânia, GO, Brasil
,
2   Instituto de Neurologia de Goiânia, Departamento de Neurologia, Goiânia, GO, Brasil
,
1   Universidade Federal de Goiás, Faculdade de Medicina, Disciplina de Neurologia, Goiânia, GO, Brasil
6   Universidade Federal do Estado do Rio de Janeiro, Neurologia, Rio de Janeiro, RJ, Brasil
,
1   Universidade Federal de Goiás, Faculdade de Medicina, Disciplina de Neurologia, Goiânia, GO, Brasil
› Author Affiliations

ABSTRACT

Multiple sclerosis (MS) prevalence, in some cities in Brazil, was estimated and was found to range from 0.75 to 30.7/100,000. The reasons for such a large variation in rates of prevalence are not clear, but environment and genetics help to explain this phenomenon.

Methods: A cross-sectional study using three sources of case ascertainment to estimate the prevalence of MS in the city of Goiânia in December, 2015.

Results: A total of 318 MS patients was found after removing overlapping sources. The prevalence of MS was 22.4/100,000 population.

Conclusion: Our study was the first in Goiás and the third in the midwest region, and we found a great increase in the prevalence of MS in the region. It is necessary to perform other studies using the same methodology for a more accurate evaluation of the true prevalence of MS in Brazil.

RESUMO

A prevalência de esclerose múltipla (EM) no Brasil foi estimada em algumas cidades e foi encontrada entre 0,75 e 30,7 / 100.000. As razões para tal grande variação nas taxas de prevalência não são claras, mas existem aspectos ambientais e genéticos para explicar esse fençmeno.

Métodos: Foram utilizadas três fontes de averiguação de casos para estimar a prevalência de esclerose múltipla (EM) no município de Goiânia em dezembro de 2015.

Resultados: Foram encontrados 318 casos de EM, retirando as sobreposições de fontes. A prevalência foi de 22,4 / 100.000.

Conclusão: Nosso estudo foi o primeiro em Goiás e o terceiro na Região Centro-Oeste, e encontrou um grande aumento na prevalência de EM na região. É necessário realizar outros estudos utilizando a mesma metodologia para uma melhor avaliação da real prevalência da EM no Brasil.



Publication History

Received: 20 September 2018

Accepted: 10 January 2019

Article published online:
16 August 2023

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  • References

  • 1 Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011 Feb;69(2):292-302. https://doi.org/10.1002/ana.22366
  • 2 Kurtzke JF. Epidemiologic contributions to multiple sclerosis: an overview. Neurology. 1980 Jul;30(7 Pt 2):61-79. https://doi.org/10.1212/WNL.30.7_Part_2.61
  • 3 Wade BJ. Spatial analysis of global prevalence of multiple sclerosis suggests need for an updated prevalence scale. Mult Scler Int. 2014;2014:124578. https://doi.org/10.1155/2014/124578
  • 4 Instituto Brasileiro de Geografia e Estatística – IBGE. Cidades. 2010 [cited 2018 Sep 4]. Available from: http://ibge-cidades.gov.br
  • 5 Ferreira MLB, Machado MIM, Vilela ML, Guedes MJ, Ataíde L., Santos S, et al. Epidemiology of 118 cases of multiple sclerosis with a 15-year follow-up in the referral center of the Hospital of Restoration, São Paulo, MG, Brazil. of Pernambuco. Arq Neuropsiquiatr. 2004 Dec;62(4)1027-32. http://dx.doi.org/10.1590/S0004-282X2004000600018
  • 6 Finkelsztejn A, Lopes JS, Noal J, Finkelsztejn JM. The prevalence of multiple sclerosis in Santa Maria, Rio Grande do Sul, Brazil. Arq Neuropsiquiatr. 2014 Feb;72(2):104-6. https://doi.org/10.1590/0004-282X20130216
  • 7 Calmon AB, Pereira F, Marin B, Preux PM, Alvarenga RP. Prevalence of multiple sclerosis in the City of Volta Redonda - Rio De Janeiro, Brazil using the capture-recapture method. Neuroepidemiology. 2016;46(2):88-95. https://doi.org/10.1159/000442471
  • 8 GOIÂNIA. P. Dados gerais. Prefeitura de Goiânia. 2018 [cited 2018 Sep 5]. Available from: http://www4.goiania.go.gov.br/portal/goiania.shtml
  • 9 Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983 Mar;13(3):227-31. https://doi.org/10.1002/ana.410130302
  • 10 IBM CORP. IBM SPSS statistics for windows: Version, v. 25.0. 2017 [cited 2017 Aug]. Available from: https://www.ibm.com/br-pt/products?lnk=fdi
  • 11 Instituto Brasileiro de Geografia e Estatística – IBGE. Censo demográfico de 2015. [cited 2018 Sep 5]. Available from: http://www.ibge.gov.br
  • 12 Pereira AB. Prevalence and incidence of multiple sclerosis in the city of Volta Redonda in the State of Rio de Janeiro [dissertation]. Universidade Federal do Rio de Janeiro, 2015.
  • 13 Pereira ABCN, Lacativa MCS, Pereira FFC, Papais-Alvarenga RM. Prevalence of multiple sclerosis in Brazil: a systematic review. Mult Scler Relat Disord. 2015 Nov;4(6):572-9. https://doi.org/10.1016/j.msard.2015.08.004
  • 14 Callegaro D, Lolio CA, Radvany J, Tilbery CP, Mendonça RA, Melo AC. Prevalence of multiple sclerosis in the city of São Paulo, Brazil, in 1990. Neuroepidemiology. 1992;11(1):11-4. https://doi.org/10.1159/000110901
  • 15 Callegaro D, Goldbaum M, Morais L, Tilbery CP, Moreira MA, Gabbai AA, et al. The prevalence of multiple sclerosis in the city of São Paulo, Brazil, 1997. Acta Neurol Scand. 2001 Oct;104(4):208-13. https://doi.org/10.1034/j.1600-0404.2001.00372.x
  • 16 Fragoso YD, Brooks JB. The prevalence of multiple sclerosis in the city of Santos has remained unaltered for five years. Arq Neuropsiquiatr. 2012 Jul;70(7):562.https://doi.org/10.1590/S0004-282X2012000700025
  • 17 Fragoso YD, Peres M. Prevalence of multiple sclerosis in the city of Santos, SP. Rev Bras Epidemiol. 2007;10(4):479-82. https://doi.org/10.1590/S1415-790X2007000400005
  • 18 Gama PD, Trigo LX, Andrade CR, Sala CR. Epidemiological study of multiple sclerosis in the city of Sorocaba, Brazil. Arq Neuropsiquiatr. 2004;62(Suppl 1):S13.
  • 19 Lacativa CM, Naylor R, et al. Multiple sclerosis in the city of Rio de Janeiro. LACTRIMS 2012. Abstracts of the Latin American Committee for Treatment and Research in Multiple Sclerosis. Rio de Janeiro, Brazil: November 2012. Mult Scler J. 2012;18 S5:1850.
  • 20 Lana-Peixoto MA, Frota ER, Campos GB, Monteiro LP; Brazilian Committee for Treatment and Research in Multiple Sclerosis. The prevalence of multiple sclerosis in Belo Horizonte, Brazil. Arq Neuropsiquiatr. 2012 Feb;70(2):102-7. https://doi.org/10.1590/S0004-282X2012000200006
  • 21 Pereira, A. B. C. N. G.; Costa, F. F. C. et al. Epidemiological Study on Multiple Sclerosis and NeuromyelittisOptica in SulFluminense Region in Rio de Janeiro State - Brazil. LACTRIMS 2012. Abstracts of the Latin American Committee for Treatment and Research in Multiple Sclerosis. Rio de Janeiro, Brazil: November 2012. Mult Scler J. 2012;18(5):1837.
  • 22 Ribeiro SB, Maia DF, Ribeiro JB, Cardoso FA, Silva C. Clinical and epidemiological profile of patients with multiple sclerosis in Uberaba, Minas Gerais, Brazil. Arq Neuropsiquiatr. 2011 Apr;69(2a 2A):184-7. https://doi.org/10.1590/S0004-282X2011000200008PMID:21537557
  • 23 Rocha FC, Herrera LC, Morales RR. Multiple sclerosis in Botucatu, Brazil; a population study. Mult Scler. 2002;8:S412.
  • 24 Dias E, Melges LD. Multiple sclerosis: a prevalence study in the São Paulo Midwestern state. Arq Neuropsiquiatr. 2006;64(1):132. Arq.Neuropsquiatr. 2006;64 (supl 1):132.
  • 25 Peruchi MM, Lin J, Lin K, Eckeli AL, Dach F, Leal AG, Machado SCN, Sá PND. Clinical and demographic characteristics of multiple sclerosis in Florianópolis, SC, Brazil. Arq Neuropsiquiatr. 2004;62(supl 2):171.
  • 26 Portela LBBB, Andrade TVF, Borralho WM, Ximenes WN, Dias-Tosta E. Epidemiologic study of the multiple sclerosis in the Distrito Federal, Brazil. Arq Neuropsiquiatr. 2004;62(supl 2):170.
  • 27 Grzesiuk AK, Siqueira HH, Silva NM, Catarino KC, Martins PM. [Prevalence of multiple sclerosis in the city of Cuiabá-MT- 2007]. O Dendrito. 2008;14(3):35-7. Portuguese.