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DOI: 10.15654/TPK-140877
Katarakt bei Hunden – Überblick und Orientierungshilfe für die Therapieentscheidung
Cataracts in dogs – overview and guideline for decision making in treatmentPublication History
Eingegangen:
29 September 2014
Akzeptiert nach Revision:
05 November 2014
Publication Date:
08 January 2018 (online)
Zusammenfassung
Die Katarakt ist die häufigste Ursache für Visuseinschränkungen und Blindheit beim Hund. Eine Linsentrübung lässt sich mittlerweile mit sehr gutem direktem Erfolg (90–95%) operieren, wobei die Auswahl geeigneter Patienten den Operationserfolg maßgeblich beeinflusst. Nach Darstellung anatomischer und physiologischer Besonderheiten der Linse wird detailliert auf die Ätiologie der Katarakt und ihre Begleiterkrankungen eingegangen. Es folgt eine Erläuterung der präoperativen Untersuchungsschritte mit Hinweis auf entscheidende Kriterien für die Auswahl der für eine Operation in Betracht kommenden Patienten. Ziel dieses Artikels ist, anhand von Orientierungshilfen bei der Diagnostik die Therapieentscheidung sowie die Bestimmung eines geeigneten Operationszeitpunkts zu erleichtern.
Summary
Cataract is the leading cause of impaired vision and vision loss in dogs. Because of the considerable progress in cataract surgery in recent decades, lens opacities can now be operated on with very good short-term success (90–95%), taking into account that proper patient selection is essential to maximize the probability of a successful surgical outcome. Following a description of anatomical and physiological lens characteristics, the etiology and complications of untreated cataracts are discussed. Furthermore, specific criteria for patient selection are addressed while delineating essential steps of the examination. This article aims to aid decision making in cataract therapy on the basis of diagnostic guidance and to facilitate the selection of an appropriate point of time for surgery.
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Literatur
- 1 Asano N, Schlötzer-Schrehardt U, Dörfler S, Naumann GO. Ultrastructure of contusion cataract. Arch Ophthalmol 1995; 113 (02) 210-215.
- 2 Barnett KC. Types of cataract in the dog. J Am Anim Hosp Assoc 1971; 08: 2-9.
- 3 Barnett KC. Inherited eye disease in the dog and cat. J Small Anim Pract 1988; 29 (07) 462-475.
- 4 Barnett KC. Hereditary cataract in the dog. J Small Anim Pract 1978; 19 1-12 109-120.
- 5 Beam S, Correa MT, Davidson MG. A retrospective-cohort study on the development of cataracts in dogs with diabetes mellitus: 200 cases. Vet Ophthalmol 1999; 02 (03) 169-172.
- 6 Bell CM, Pot SA, Dubielzig RR. Septic implantation syndrome in dogs and cats: a distinct pattern of endophthalmitis with lenticular abscess. Vet Ophthalmol 2013; 16 (03) 180-185.
- 7 Boroffka SAEB, Verbruggen A-MJ, Boeve MH, Stades FC. Ultrasonographic diagnosis of persistent hyperplastic tunica vasculosa lentis/persistent hyperplastic primary vitreous in two dogs. Vet Radiol Ultrasound 1998; 39 (05) 440-444.
- 8 Braus BK. Die Augenuntersuchung bei Kleintieren Tierärztl Prax 2012; 40 (K): 447-456.
- 9 Braus BK, Rhodes M, Featherstone HJ, Renwick PW, Heinrich CL. Cataracts are not associated with retinal detachment in the Bichon Frise in the UK – a retrospective study of preoperative findings and outcomes in 40 eyes. Vet Ophthalmol 2012; 15 (02) 98-101.
- 10 Burnat K, Van Der Gucht E, Waleszczyk WJ, Kossut M, Arckens L. Lack of early pattern stimulation prevents normal development of the alpha (Y) retinal ganglion cell population in the cat. J Comp Neurol 2012; 520 (11) 2414-2429.
- 11 Cook C, Davidson M, Brinkmann M, Priehs D, Abrams K, Nasisse M. Diode laser transscleral cyclophotocoagulation for the treatment of glaucoma in dogs: results of six and twelve month follow-up. Vet Comp Ophthalmol 1997; 07: 148-154.
- 12 Da Costa P, Merideth RE, Sigler RL. Cataracts in dogs after long-term ketoconazole therapy. Vet Comp Ophthalmol 1996; 06: 176-180.
- 13 Cullen CL, Ihle SL, Webb AA, Mccarville C. Keratoconjunctival effects of diabetes mellitus in dogs. Vet Ophthalmol 2005; 08 (04) 215-224.
- 14 Curtis R. Lens luxation in the dog and cat. Vet Clin North Am Small Anim Pract 1990; 20 (03) 755-773.
- 15 Curtis R, Barnett KC. Primary lens luxation in the dog. J Small Anim Pract 1980; 21 (12) 657-668.
- 16 Curtis R, Barnett K, Leon A. Persistent hyperplastic primary vitreous in the Staffordshire bull terrier. Vet Rec 1984; 115 (15) 385.
- 17 Davidson MG, Nasisse MP. Traumatic anterior lens capsule disruption. J Am Anim Hosp Assoc 1991; 27: 410-414.
- 18 Davidson MG, Nelms SR. Diseases of the canine lens and cataract formation. In: Veterinary Ophthalmolgy. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 1199-1233.
- 19 Denis HM, Brooks DE, Alleman AR, Andrew SE, Plummer C. Detection of anti-lens crystallin antibody in dogs with and without cataracts. Vet Ophthalmol 2003; 06 (04) 321-327.
- 20 Donaldson D, Sansom J, Adams V. Canine limbal melanoma: 30 cases (1992–2004). Part 2. Treatment with lamellar resection and adjunctive strontium-90beta plesiotherapy – efficacy and morbidity. Vet Ophthalmol 2006; 09 (03) 179-185.
- 21 Eagle R, Spencer W. Lens. In: Ophthalmic Pathology. Spencer W. ed. Philadelphia: Saunders; 1995: 372-427.
- 22 Gelatt KN. Pediatric ophthalmology in small animal practice. Vet Clin North Am 1973; 03 (03) 321-333.
- 23 Gelatt KN, MacKay EO. Secondary glaucomas in the dog in North America. Vet Ophthalmol 2004; 07 (04) 245-259.
- 24 Gelatt KN, Wallace MR, Andrew SE, MacKay EO, Samuelson DA. Cataracts in the Bichon Frise. Vet Ophthalmol 2003; 06 (01) 3-9.
- 25 Gerson RJ, MacDonald JS, Alberts AW, Chen J, Yudkovitz JB, Greenspan MD. et al. On the etiology of subcapsular lenticular opacities produced in dogs receiving HMG-CoA reductase inhibitors. Exp Eye Res 1990; 50 (01) 65-78.
- 26 Gimbel H. Intraoperative management of posterior capsule tears in phacoemulsification and intraocular lens implantation. Ophthalmology 2001; 108 (12) 2186-2189.
- 27 Grahn BH, Peiffer RL. Fundamentals of veterinary ophthalmic pathology. In: Veterinary Ophthalmology. 4th. edn. Gelatt KN. ed. Ames: Blackwell; 2007: 355-437.
- 28 Gum GG, MacKay EO. Physiology of the eye. In: Veterinary Ophthalmology. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 171-207.
- 29 Gwin R, Lerner I, Warren J, Gum G. Decrease in canine corneal endothelial cell density and increase in corneal thickness as functions of age. Invest Ophthalmol Vis Sci 1982; 22 (02) 267-271.
- 30 Gwin R, Warren J, Samuelson D, Gum G. Effects of phacoemulsification and extracapsular lens removal on corneal thickness and endothelial cell density in the dog. Invest Ophthalmol Vis Sci 1983; 24 (02) 227-236.
- 31 Hardman C, Stanley RG. Diode laser transscleral cyclophotocoagulation for the treatment of primary glaucoma in 18 dogs: a retrospective study. Vet Ophthalmol 2001; 04 (03) 209-215.
- 32 Heldt H. Untersuchungen zur Progression der Katarakt beim Hund sowie Ermittlung der Behandlungsergebnisse nach Kataraktoperationen. Diss med vet, Tierärztliche Hochschule Hannover. 2006
- 33 Hendrix DVH. Outcomes of dogs presented for cataract evaluation: A retrospective study. J Am Anim Hosp Assoc 2005; 41 (04) 235-240.
- 34 Herring IP. Clinical pharmacology and therapeutics part 4: Mydriatics/ cycloplegics, anesthetics, and tear substitutes and stimulators. In: Veterinary Ophthalmolgy. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 423-434.
- 35 Jamieson V, Davidson M. Ocular complications following cobalt 60 radiotherapy of neoplasms in the canine head region. J Am Anim Hosp Assoc 1991; 27 (01) 51-55.
- 36 Kador PF, Betts D, Wyman M, Blessing K, Randazzo J. Effects of topical administration of an aldose reductase inhibitor on cataract formation in dogs fed a diet high in galactose. Am J Vet Res 2006; 67 (10) 1783-1787.
- 37 Kador PF, Webb TR, Bras D, Ketring K, Wyman M. Topical KINOSTATTM ameliorates the clinical development and progression of cataracts in dogs with diabetes mellitus. Vet Ophthalmol 2010; 13 (06) 363-368.
- 38 Keil S, Davidson H. Canine cataracts: A review of diagnostic and treatment procedure. Vet Med 2001; 96: 14-38.
- 39 Kelman CD. Phaco-emulsification and aspiration. A new technique of cataract removal. A preliminary report. Am J Ophthalmol 1967; 64 (01) 23-35.
- 40 Klein HE, Krohne SG, Moore GE, Stiles J. Postoperative complications and visual outcomes of phacoemulsification in 103 dogs (179 eyes): 2006–2008. Vet Ophthalmol 2011; 14 (02) 114-120.
- 41 Leasure J, Gelatt KN, MacKay EO. The relationship of cataract maturity to intraocular pressure in dogs. Vet Ophthalmol 2001; 04 (04) 273-276.
- 42 Lim CC, Bakker SC, Waldner CL, Sandmeyer LS, Grahn BH. Cataracts in 44 dogs (77 eyes): A comparison of outcomes for no treatment, topical medical management, or phacoemulsification with intraocular lens implantation. Can Vet J 2011; 52 (03) 283-288.
- 43 Maehara S, Itoh N, Wakaiki S, Yamasaki A, Tsuzuki K, Izumisawa Y. The effects of cataract stage, lens-induced uveitis and cataract removal on ERG in dogs with cataract. Vet Ophthalmol 2007; 10 (05) 308-312.
- 44 Martin CL, Christmas R, Leipold HW. Formation of temporary cataracts in dogs given a disophenol preparation. J Am Vet Med Assoc 1972; 161 (03) 294-301.
- 45 Martin CL, Chambreau T. Cataract production in experimentally orphaned puppies fed a commercial replacement for bitch’s milk. J Am Anim Hosp Assoc 1982; 18: 115-119.
- 46 Miller P, Murphy C. Vision in dogs. J Am Vet Assoc 1995; 207 (12) 1623-1634.
- 47 Miller TR, Whitley RD, Meek LA, Garcia GA, Wilson MC, Rawls BH. Phacofragmentation and aspiration for cataract extraction in dogs: 56 cases (1980-1984). J Am Vet Med Assoc 1987; 190 (12) 1577-1580.
- 48 Narfström K, Petersen-Jones SM. Diseases of the canine ocular fundus. In: Veterinary Ophthalmology. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 1303-1392.
- 49 Nell B, Wollanke B, Eule C. Untersuchung des Auges und seiner Adnexe. In: Klinische Propädeutik der Haus-und Heimtiere, 7. Aufl. Baumgartner W. Hrsg. Stuttgart: Parey; 2009: 400-430.
- 50 Ofri R. Lens. In: Slatter’s Fundamentals of Veterinary Ophthalmology. 5th. edn. Maggs DJ, Miller PE, Ofri R. eds. St. Louis: Elsevier; 2013: 272-298.
- 51 Paulsen ME, Kass PH. Traumatic corneal laceration with associated lens capsule disruption: a retrospective study of 77 clinical cases from 1999 to 2009. Vet Ophthalmol 2012; 15 (06) 355-368.
- 52 Paulsen ME, Lavach JD, Severin GA, Eichenbaum JD. The effect of lens-induced uveitis on the success of extracapsular cataract extraction: A retrospective study of 65 lens removals in the dog. J Am Anim Hosp Assoc 1986; 22 (01) 49-56.
- 53 Peiffer RL. Ophthalmologie bei Kleintieren, 1. Aufl. Stuttgart: Schattauer; 1991
- 54 Peng Q, Visessook N, Apple DJ, Pandey SK, Werner L, Escobar-Gomez M. et al. Surgical prevention of posterior capsule opacification. Part 3: Intraocular lens optic barrier effect as a second line of defense. J Cataract Refract Surg 2000; 26 (02) 198-213.
- 55 Playter RF. Development and maturation of a cataract. J Am Anim Hosp Assoc 1977; 13: 917-922.
- 56 Plummer C, Regnier A, Gelatt KN. The canine glaucomas. In: Veterinary Ophthalmology. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 1050-1145.
- 57 Pyrah IT, Kalinowski A, Jackson D, Davies W, Davis S, Aldridge A. et al. Toxicologic lesions associated with two related inhibitors of oxidosqualene cyclase in the dog and mouse. Toxicol Pathol 2001; 29 (02) 174-179.
- 58 Roberts SM, Lavach JD, Severin GA, Withrow SJ, Gillette EL. Ophthalmic complications following megavoltage irradiation of the nasal and paranasal cavities in dogs. J Am Vet Med Assoc 1987; 190 (01) 43-47.
- 59 Rose MD, Mattoon JS, Gemensky-Metzler AJ, Wilkie DA, Rajala-Schultz PJ. Ultrasound biomicroscopy of the iridocorneal angle of the eye before and after phacoemulsification and intraocular lens implantation in dogs. Am J Vet Res 2008; 69 (02) 279-288.
- 60 Rubin LF, Gelatt KN. Spontaneous resorption of the cataractous lens in dogs. J Am Vet Med Assoc 1968; 152 (02) 139-153.
- 61 Rubin LF, Mattis PA. Dimethyl sulfoxide: lens changes in dogs during oral administration. Science 1966; 153 3731 83-84.
- 62 Samuelson DA. Ophthalmic anatomy. In: Veterinary Ophthalmology. 5th. edn. Gelatt KN, Gliger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 39-170.
- 63 Schiavo DM, Field WE, Vymetal FJ. Cataracts in beagle dogs given diazoxide. Diabetes 1975; 24 (12) 1041-1049.
- 64 Schmidt GM, Vainisi SJ. Retrospective study of prophylactic random transscleral retinopexy in the Bichon Frise with cataract. Vet Ophthalmol 2004; 07 (05) 307-310.
- 65 Sigle KJ, Nasisse MP. Long-term complications after phacoemulsification for cataract removal in dogs: 172 cases (1995-2002). J Am Vet Med Assoc 2006; 228 (01) 74-79.
- 66 Stades FC. Persistent hyperplastic tunica vasculosa lentis and persistent hyperplastic primary vitreous in Doberman Pinschers: techniques and results of surgery. J Am Anim Hosp Assoc 1983; 19: 393-402.
- 67 Stades FC. Persistent hyperplastic tunica vasculosa lentis and persistent hyperplastic primary vitreous (PHTVL/PHPV) in 90 closely related Doberman Pinschers: clinical aspects. J Am Anim Hosp Assoc 1980; 16 (05) 739-751.
- 68 Susick RL, Jordan RA, Watkins JR. Cataracts in dogs following subchronic administration of the phenylpiperazine antihypertensive agent PD 78787. Fundam Appl Toxicol 1991; 17 (03) 593-600.
- 69 Vainisi SJ, Wolfer JC, Smith PJ. Surgery of the canine posterior segment. In: Veterinary Ophthalmology. 4th. edn. Gelatt KN. ed. Ames: Blackwell; 2007: 1026-1158.
- 70 Walde I. Linse. In: Operationen an Hund und Katze, 2. Aufl. Schebitz H, Brass W. Hrsg. Berlin: Parey; 1999: 159-164.
- 71 Walde I, Nell B, Schäffer EH, Köstlin R. Hrsg. Linse. In: Augenheilkunde Lehrbuch und Atlas, 3. Aufl. Stuttgart: Schattauer; 2008: 319-372.
- 72 Wilcock BP, Peiffer RL. The pathology of lens-induced uveitis in dogs. Vet Pathol 1987; 24 (06) 549-553.
- 73 Wilkie DA, Colitz CMH. Update on veterinary cataract surgery. Curr Opin Ophthalmol 2009; 20 (01) 61-68.
- 74 Wilkie DA, Colitz CMH. Surgery of the lens. In: Veterinary Ophthalmology. 5th. edn. Gelatt KN, Gilger BC, Kern TJ. eds. Ames: Wiley-Blackwell; 2013: 1234-1278.
- 75 Wilkie DA. Cataract surgery: challenges and complications: Part I. Henningsdorf: Acrivet Course (Intraocular surgery for advanced surgeons); 2014: 1-8.
- 76 Wilkie DA, Colitz CMH, Bras ID, Kuonen VJ, Norris KN, Basham CR. Canine cataracts, diabetes mellitus and spontaneous lens capsule rupture: a retrospective study of 18 dogs. Vet Ophthalmol 2006; 09 (05) 328-334.
- 77 Williams DL, Boydell IP, Long RD. Current concepts in the management of canine cataract: a survey of techniques used by surgeons in Britain, Europe and the USA and a review of recent literature. Vet Rec 1996; 138: 347-353.
- 78 Van der Woerdt A, Wilkie DA, Myer CW. Ultrasonographic abnormalities in the eyes of dogs with cataracts: 147 cases (1986-1992). J Am Vet Med Assoc 1993; 203 (06) 838-841.
- 79 Van der Woerdt A, Nasisse MP, Davidson MG. Lens-induced uveitis in dogs: 151 cases (1985-1990). J Am Vet Assoc 1992; 201: 921-926.
- 80 Van der Woerdt A. Lens-induced uveitis. Vet Ophthalmol 2000; 03 (04) 227-234.
- 81 Zahn K, Köstlin R. Zur Linsenchirurgie beim Hund – retround prospektive Auswertung von 230 Augenoperationen. Tierärztl Prax 2001; 29 (K): 164-172.
- 82 Zigler JS, Hess HH. Cataracts in the Royal College of Surgeons rat: Evidence for initiation by lipid peroxidation products. Exp Eye Res 1985; 41 (01) 67-76.