Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035024.xml
Thromb Haemost 2015; 113(01): 209-211
DOI: 10.1160/TH14-03-0285
DOI: 10.1160/TH14-03-0285
Letter to the Editor
Thrombin generation in the presence of platelets is sensitive to the activation status of von Willebrand factor
Financial support: BDL, LP and HK were supported in part by the Dutch Heart Foundation (NHS2006T053;NHS2006T5301).Further Information
Publication History
Received:
28 March 2014
Accepted after major revision:
28 August 2014
Publication Date:
27 November 2017 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035024/201501/lookinside/thumbnails/10-1160-th14-03-0285-1.jpg)
-
References
- 1 Hassan MI, Saxena A, Ahmad F. Structure and function of von Willebrand factor. Blood coagulation & fibrinolysis: an international journal in haemostasis and thrombosis 2012; 23: 11-22.
- 2 Beguin S, Kumar R, Keularts I. et al. Fibrin-dependent platelet procoagulant activity requires GPIb receptors and von Willebrand factor. Blood 1999; 93: 564-570.
- 3 Lenting PJ, Casari C, Christophe OD. et al. von Willebrand factor: the old, the new and the unknown. J Thromb Haemost 2012; 10: 2428-2437.
- 4 Huizinga EG, Tsuji S, Romijn RA. et al. Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain. Science 2002; 297: 1176-1179.
- 5 Sadler JE. Biomedicine. Contact--how platelets touch von Willebrand factor. Science 2002; 297: 1128-1129.
- 6 Keuren JF, Baruch D, Legendre P. et al. von Willebrand factor C1C2 domain is involved in platelet adhesion to polymerized fibrin at high shear rate. Blood 2004; 103: 1741-1746.
- 7 Rugeri L, Beguin S, Hemker C. et al. Thrombin-generating capacity in patients with von Wille-brand‘s disease. Haematologica 2007; 92: 1639-1646.
- 8 Ribba AS, Voorberg J, Meyer D. et al. Characterisation of recombinant von Willebrand factor corresponding to mutations in type IIA and type IIB von Willebrand disease. J Biol Chem 1992; 267: 23209-23215.
- 9 Hemker HC, Giesen P, Al Dieri R. et al. Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003; 33: 4-15.
- 10 Hulstein JJ, Lenting PJ, de Laat B. et al. beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation. Blood 2007; 110: 1483-1491.
- 11 Stel HV, Sakariassen KS, Scholte BJ. et al. Characterisation of 25 monoclonal antibodies to factor VIII-von Willebrand factor: relationship between ristocetin-induced platelet aggregation and platelet adherence to subendothelium. Blood 1984; 63: 1408-1415.