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Thromb Haemost 2013; 110(01): 199-201
DOI: 10.1160/TH13-02-0123
Letters to the Editor
Schattauer GmbH

Simultaneous measurement of ATP release and LTA does not potentiate platelet aggregation to epinephrine

Marie Lordkipanidzé   *
1   Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
,
Gillian C. Lowe   *
1   Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
,
Steve P. Watson
1   Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
,
on behalf of the UK GAPP study group › Author Affiliations Financial support: SPW holds a BHF chair (CH/03/003). ML is supported by the Canadian Institute of Health Research (MFE-107592) and the British Heart Foundation (PG/11/31/28835). GL is supported by the Wellcome Trust (093994).
Further Information

Publication History

Received: 13 February 2013

Accepted after major revision: 20 April 2013

Publication Date:
30 November 2017 (online)

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* These authors contributed equally to this work and share first authorship.


 

  • References

  • 1 Hayward CP, Moffat KA, Castilloux JF. et al. Simultaneous measurement of adenosine triphosphate release and aggregation potentiates human platelet aggregation responses for some subjects, including persons with Quebec platelet disorder. Thromb Haemost 2012; 107: 726-734.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Harrison P, Mackie I, Mumford A. et al. Guidelines for the laboratory investigation of heritable disorders of platelet function. Br J Haematol 2011; 155: 30-44.
    CrossrefPubMedGoogle Scholar
  • 3 Pai M, Wang G, Moffat KA. et al. Diagnostic usefulness of a lumi-aggregometer adenosine triphosphate release assay for the assessment of platelet function disorders. Am J Clin Pathol 2011; 136: 350-358.
    CrossrefPubMedGoogle Scholar
  • 4 Nieuwenhuis HK, Akkerman JW, Sixma JJ. Patients with a prolonged bleeding time and normal aggregation tests may have storage pool deficiency: studies on one hundred six patients. Blood 1987; 70: 620-623.
    PubMedGoogle Scholar
  • 5 Dawood BB, Lowe GC, Lordkipanidzé M. et al. Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel. Blood 2012; 120: 5041-5049.
    CrossrefPubMedGoogle Scholar
  • 6 Callan MB, Shofer FS, Wojenski C. et al. Chronolume and magnesium potentiate aggregation of canine but not human platelets in citrated plateletrich plasma. Thromb Haemost 1998; 80: 176-180.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 7 Mehta P, Mehta J, Ostrowski N. et al. Potentiation of platelet aggregation by Chronolume. Thromb Res 1983; 32: 509-512.
    CrossrefPubMedGoogle Scholar
  • 8 Zwierzina WD, Kunz F. A method of testing platelet aggregation in native whole blood. Thromb Res 1985; 38: 91-100.
    CrossrefPubMedGoogle Scholar
  • 9 Pfueller SL, Broadway M. Inhibition of platelet aggregation and [14C] serotonin release by luciferin: luciferase preparations. Thromb Res 1986; 44: 539-542.
    CrossrefPubMedGoogle Scholar
  • 10 Thompson NT, Scrutton MC. Inhibition by luciferin-luciferase reagents of aggregatory responses to excitatory agonists in washed platelet suspensions. Thromb Res 1985; 38: 109-119.
    CrossrefPubMedGoogle Scholar
  • 11 Nash CA, Severin S, Dawood BB. et al. Src family kinases are essential for primary aggregation by G(i) -coupled receptors. J Thromb Haemost 2010; 08: 2273-2282.
    CrossrefPubMedGoogle Scholar