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Thromb Haemost 2011; 106(06): 1076-1083
DOI: 10.1160/TH11-06-0382
Blood Coagulation, Fibrinolysis and Cellular Haemostasis
Schattauer GmbH

Antithrombin-independent thrombin inhibitors, but not direct factor Xa inhibitors, enhance thrombin generation in plasma through inhibition of thrombin-thrombomodulin-protein C system

Taketoshi Furugohri
1   Biological Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan
,
Nobutoshi Sugiyama
1   Biological Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan
,
Yoshiyuki Morishima
1   Biological Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan
,
Toshiro Shibano
1   Biological Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan
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