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Thromb Haemost 2007; 97(03): 343-347
DOI: 10.1160/TH06-09-0488
DOI: 10.1160/TH06-09-0488
Theme Issue Article
Protein C inhibitor, a serpin with functions in- and outside vascular biology
Weitere Informationen
Publikationsverlauf
Received
01. September 2006
Accepted
14. Februar 2006
Publikationsdatum:
28. November 2017 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035024/200703/lookinside/thumbnails/10-1160-th06-09-0488-1.jpg)
Summary
Human protein C inhibitor (PCI), a serpin-type protease inhibitor originally described as an inhibitor of activated protein C, has broad protease reactivity. In addition to its activities within the blood clotting and fibrinolytic cascades, it seems to participate in several biological processes including reproductiorn and tumor growth. This review summarizes the current understanding of PCI function, regulation, and potential biological role.
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