CC BY-NC-ND-license · Joints 2016; 04(04): 228-235
DOI: 10.11138/jts/2016.4.4.228
Original Article
Georg Thieme Verlag KG Stuttgart · New York

The prospective opportunities offered by magnetic scaffolds for bone tissue engineering: a review

Alessandro Ortolani
1   Laboratory of Nano Biotechnology (NaBI), Istituto Ortopedico Rizzoli, Bologna, Italy
,
Michele Bianchi
1   Laboratory of Nano Biotechnology (NaBI), Istituto Ortopedico Rizzoli, Bologna, Italy
,
Massimiliano Mosca
2   I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy
,
Silvio Caravelli
2   I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy
,
Mario Fuiano
2   I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy
,
Maurilio Marcacci
1   Laboratory of Nano Biotechnology (NaBI), Istituto Ortopedico Rizzoli, Bologna, Italy
2   I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy
,
Alessandro Russo
1   Laboratory of Nano Biotechnology (NaBI), Istituto Ortopedico Rizzoli, Bologna, Italy
2   I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy
› Author Affiliations
Further Information

Publication History

Publication Date:
15 September 2017 (online)

Abstract

Magnetic scaffolds are becoming increasingly attractive in tissue engineering, due to their ability to enhance bone tissue formation by attracting soluble factors, such as growth factors, hormones and polypeptides, directly to the implantation site, as well as their potential to improve the fixation and stability of the implant. Moreover, there is increasing evidence that the synergistic effects of magnetic scaffolds and magnetic fields can promote bone repair and regeneration. In this manuscript we review the recent innovations in bone tissue engineering that exploit magnetic biomaterials combined with static magnetic fields to enhance bone cell adhesion and proliferation, and thus bone tissue growth.