Total endoscopic eradication of Barrett's esophagus: Study methodology, candidate selection, and clinical outcomes

Introduction

This issue of Endoscopy focuses on total endoscopic eradication of Barrett's esophagus, a condition described by the Australian surgeon Norman Rupert Barrett in 1950 [1] . This paper considers methodological aspects of studies of ablative therapies for Barrett's esophagus, and how the choices made by investigators with respect to study methodology and candidate selection might impact the clinical outcomes observed in these studies.

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