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DOI: 10.1055/s-2008-1077619
© Georg Thieme Verlag KG Stuttgart · New York
Endoscopic resection of sporadic duodenal adenomas: an efficient technique with a substantial risk of delayed bleeding
Publikationsverlauf
submitted 21 October 2007
accepted after revision 16 July 2008
Publikationsdatum:
30. September 2008 (online)
![](https://www.thieme-connect.de/media/endoscopy/200810/lookinside/thumbnails/10.1055-s-2008-1077619-1.jpg)
Introduction: Data on endoscopic resection of sporadic duodenal adenoma (SDA) are sparse; we present our results concerning safety and efficacy in a retrospective analysis of saline-assisted endoscopic resection of SDA.
Patients and methods: The cases of all patients who underwent endoscopic resection for SDA between May 1998 and May 2006 were analyzed. Endoscopic resection was carried out using standard injection and cut methods. In some patients hemoclips and argon plasma coagulation were used, either for prophylaxis or for the treatment of procedure-related bleeding.
Results: Thirty-six patients with a total of 37 lesions (mean size 19 mm, range 4 – 50 mm) were analyzed. Lesions larger than 20 mm were more frequently resected piecemeal (P = 0.022). Intraprocedural bleeding occurred in 14 % of cases, without any significant association with lesion size or the resection technique. One fatal perforation occurred. Macroscopically complete resection was achieved in 97 % of cases, as confirmed by at least one negative control endoscopy with biopsies after a mean follow-up of 15 months. Although clipping and argon plasma coagulation were not applied in any systematic way, it was noticeable that in the 20 cases in which they were used for hemostasis or prevention, no delayed bleeding was observed after the procedures. In contrast, bleeding occurred in 22 % of the 23 procedures performed without these additional techniques.
Conclusion: Endoscopic resection is an efficient and acceptably safe technique for treating SDA. Further studies need to assess whether systematic bleeding prophylaxis will reduce the incidence of delayed hemorrhage after endoscopic resection.
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V. Lépilliez, MD
Service d’Hépatogastroentérologie
Hôpital Edouard Herriot
Place d’Arsonval
69437 Lyon Cedex 03
France
Fax: +33-4-72110147
eMail: lepilliezvincent@orange.fr