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DOI: 10.1055/s-2008-1077238
© Georg Thieme Verlag KG Stuttgart · New York
Pflanzliche Sterole als Nahrungsmitteladditiva zur Prävention kardiovaskulärer Erkrankungen
Plant sterols as dietary supplements for the prevention of cardiovascular diseasesPublikationsverlauf
eingereicht: 9.11.2007
akzeptiert: 14.4.2008
Publikationsdatum:
20. Mai 2008 (online)
Zusammenfassung
Sterol-angereichtere Nahrungsmittel „Functional Foods” werden zur Senkung des Cholesterinspiegels von vielen Menschen konsumiert. Ein Wirksamkeitsbeleg von Phytosterolen im Hinblick auf kardiovaskuläre Ereignisse liegt nicht vor. Das Krankheitsbild der Sitosterolämie, epidemiologische Daten und neue experimentelle Ergebnisse ergeben Hinweise, dass pflanzliche Sterole negative kardiovaskuläre Effekte induzieren könnten. Vor einer generellen Empfehlung dieser Produkte sind daher weitere Daten zur Wirksamkeit und Sicherheit erforderlich.
Summary
„Functional foods” supplemented with plant sterols are advertised and added to regular meals to reduce serum cholesterol concentrations. The effects of increased phytosterol levels on cardiovascular diseases, however, are not known. Findings in patients with sitosterolemia, data from epidemiological studies, and experimental data from animal studies suggest that plant sterols may potentially exert negative cardiovascular effects. Additional studies investigating relevant clinical endpoints are needed before a diet supplemented with plant sterols can be recommended in the prevention of cardiovascular diseases.
Schlüsselwörter
pflanzliche Sterole - Prävention - Ernährung - kardiovaskuläres Risiko - Nahrungsergänzungsstoffe
Key words
plant sterols - prevention - nutrition - cardiovascular risk - functional food
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Dr. med. Oliver Weingärtner
Universitätsklinikum des Saarlandes, Abteilung für Kardiologie, Angiologie und internistische Intensivmedizin
Kirrberger Strasse, Gebäude 40
66421 Homburg Saar
Telefon: 06841/1621-333
Fax: 06841/1621-331
eMail: oweingartner@aol.com