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Planta Med 1980; 40: 152-162
DOI: 10.1055/s-2008-1075019
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Algues Fixées de la Côte Atlantique Française Contenant des Substances Antimitotiques

Seaweeds of French Atlantic Coast with Antimitotic CompoundsJ. C. Chénieux1 , J. F. Verbist2 , J. F. Biarrd2 , E. Clément2 , J. Le Boterff2 , P. Maupas3 , M. Lecocq4
  • 1Laboratoire de Biologie Végétale et Cellulaire, Faculté de Pharmacie, Université de Tours,
  • 2Laboratoire de Matière Médicale, Faculté de Pharmacie, Université de Nantes,
  • 3Laboratoire de Microbiologie et Immunologie, Faculté de Pharmacie, Université de Tours,
  • 4Laboratoire de Biologie et Cytophysiologie Végétales, Faculté des Sciences, Université de Nantes.
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Publication History

Publication Date:
29 April 2008 (online)

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Abstract

89 samples (82 species) of marine algae of French Atlantic coast have been investigated in vitro for their potential antimitotic properties, by vegetable tissue culture technique (inhibition of Helian-thus tuberosus growth). For each sample, three extracts, prepared with Et20, then EtOH 99 %, then H20, have been tested. Some of the most interesting extracts have also been examinated in vitro by "Heliantbus tuberosus test-disc", by crown-gall tissue culture technique, and for their cytotoxicity on KB-cells and for their antimetabolite properties. Results

Key Word Index

Seaweeds - Antimitotic - Antitumor - Growth Inhibitor - Pharmacological Screening.