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Planta Med 1980; 40(10): 185-192
DOI: 10.1055/s-2008-1074957
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Gleditsia Saponins

I. Structures of Monoterpene Moieties of Gleditsia Saponin C1 Y. Okada, K. Koyama, K. Takahashi, T. Okuyama, S. Shibata
  • Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy
1 Present Address: Wakunaga Pharmaceutical CO. Ltd. 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima-ken 729-64 Japan. (Dedicated to Professor Dr. Kurt Mothes on the occasion of his 80th birthday)
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Publication Date:
29 April 2008 (online)

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Abstract

A major triterpenoid saponin of the fruit of Gleditsia japonica Miq. was isolated to designate gleditsia saponin C (GS-C).

On mild alkaline hydrolysis of GS-C, three monoterpene carboxylic acids (IV, VI and VII) were separated to remain a bisdesmoside, GS-C'. The structure of IV was established to be (+)2,6-dimethyl-6(S)hydroxyl-2-trans-2,7-octadienoic acid.

The compound (VII) is an artifact derived from the ester form of IV, while VI is possibly derived from (+)2-hydroxymethyl-6-methyl-6(S)-hydroxyl-2-trans-2,7-octadienoic acid (VIII) which attaches to GS-C' with an ester linkage.

Key Word Index

Gleditsia japonica - Leguminosae - Saponins - Gleditsia Saponin C - (+)2,6-Dimethyl-6(S)hydroxyl-2-trans-2,7-octadienoic Acid.