Synlett 2008(7): 1045-1049  
DOI: 10.1055/s-2008-1072652
LETTER
© Georg Thieme Verlag Stuttgart · New York

Iodine-Catalyzed Nucleophilic Substitution Reactions of Benzylic Alcohols

Pabbaraja Srihari*, Dinesh C. Bhunia, Pamu Sreedhar, Jhillu S. Yadav
Organic Division-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)27160512; e-Mail: srihari@iict.res.in;
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Publication History

Received 31 October 2007
Publication Date:
28 March 2008 (online)

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Abstract

Molecular iodine efficiently catalyzes the direct nucleophilic substitution of the hydroxy group of benzylic alcohols with carbon and oxygen nucleophiles.