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DOI: 10.1055/s-2008-1040318
Portal Hypertension and Gastrointestinal Bleeding
Publikationsverlauf
Publikationsdatum:
22. Februar 2008 (online)
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ABSTRACT
Variceal bleeding is one of the most serious complications of portal hypertension. The driving force for the development of varices is an increase in portal pressure. As portal hypertension progresses, varices dilate until they finally rupture and bleed. This sequence of events might be prevented by achieving a sufficient decrease in portal pressure or by acting locally at the varices with endoscopic treatments. This article reviews the rationale for the management of portal hypertension and the current recommendations for the prevention and treatment of variceal bleeding.
KEYWORDS
Cirrhosis - varices - endoscopic band ligation - TIPS - β-adrenergic blockers - hepatic venous pressure gradient
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174 Escorsell A, Bosch J.
Pathophysiology of variceal bleeding . In: Groszmann RJ, Bosch J Portal Hypertension in the 21st Century. Dordrecht/Boston/London; Kluwer Academic Publishers 2004: 155-166
Professor Jaime BoschM.D. Ph.D.
Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Villarroel 170
08036 Barcelona, Spain
eMail: jbosch@clinic.ub.es