Am J Perinatol 1985; 2(3): 194-197
DOI: 10.1055/s-2007-999947
ORIGINAL ARTICLE

© 1985 by Thieme Medical Publishers, Inc.

Successful Therapy of Unilateral Pulmonary Emphysema: Mechanical Ventilation with Extremely Short Inspiratory Time

William L. Meadow, David Cheromcha
  • Wyler Children's Hospital, The University of Chicago Medical Center, Chicago, Illinois
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Publikationsverlauf

Publikationsdatum:
04. März 2008 (online)

ABSTRACT

We describe a novel approach to the mechanical ventilation of two neonates with life-threatening unilateral pulmonary emphysema (UPE). Using a standard time-cycled, pressure-limited ventilator, we achieved resolution of UPE with shorter inspiratory times than previously reported effective in human newborns (0.10-0.15 sec). We elected this ventilatory strategy in order to direct tidal volume preferentially toward units of lung with relatively normal time constants, while avoiding inflation of longer time-constant emphysematous areas.