Serum Coenzyme Q10 Levels in Thyroid Disorders

F. Ogura; H. Morii; M. Ohno; T. Ueno; S. Kitabatake; N. Hamada; K. Ito

doi:10.1055/s-2007-999193

Hormone and Metabolic Research, Inhaltsverzeichnis

Horm Metab Res 1980; 12(10): 537-540
DOI: 10.1055/s-2007-999193

Serum Coenzyme Q₁₀ Levels in Thyroid Disorders

F. Ogura, H. Morii, M. Ohno, T. Ueno, S. Kitabatake¹ , N. Hamada² , K. Ito²

Second Department of Internal Medicine, Osaka City University, Abeno, Osaka, Japan
¹Statistical Laboratory, Osaka City University, Abeno, Osaka, Japan
²Ito Hospital, Shibuya, Tokyo, Japan

Abstract

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Summary

The correlation between serum CoQ₁₀ levels and serum thyroid hormones in thyroid disorders was investigated in the present studies. Serum CoQ₁₀ was measured by high speed liquid chromatography utilizing ultraviolet detector. In normal controls, serum CoQ₁₀ level of the male was higher than that of the female. Serum CoQ₁₀ level in hyperthyroidism was significantly lower than that of euthyroid subjects. But in hypothyroidism, serum CoQ₁₀ level did not show any significant difference from that of euthyroid subjects. Significant inverse correlations were demonstrated between log CoQ₁₀ and log T₃, log T₄, log free T₄, or log rT₃. These data suggested abnormalities in the mitochondrial electron transport system in thyroid disorders.

Key-Words

Serum Coenzyme Q₁₀ - Thyroid Disorders

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