Am J Perinatol 1996; 13(8): 491-494
DOI: 10.1055/s-2007-994434
ORIGINAL ARTICLE

© 1996 by Thieme Medical Publishers, Inc.

Hyperreactio Luteinalis Complicating a Normal Singleton Pregnancy

Donna S. Lambers, Barak Rosenn
  • Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio
Further Information

Publication History

Publication Date:
04 March 2008 (online)

ABSTRACT

Hyperreactio luteinalis is a rare, usually self-limited syndrome with bilaterally enlarged ovaries containing multiple theca lutein cysts. It is usually associated with ges-tational trophoblastic disease and/or pregnancies that have elevated maternal serum hCG levels. Hyperreactio luteinalis with maternal anasarca was diagnosed at 19 weeks in a spontaneously conceived gestation, in a 16-year-old primigravida. A second trimester termination for maternal respiratory decompensation secondary to pleural effusions and ascites was required. There was no evidence of trophoblastic disease on pathological examination of the products of conception. Hyperreactio luteinalis may be diagnosed prenatally by ultrasound, and intervention may be necessary for maternal indications. Following termination of pregnancy, spontaneous resolution and regression of ovarian size may be expected.