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Synfacts 2007(12): 1228-1228  
DOI: 10.1055/s-2007-991310
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (+)-Isomigrastatin

Contributor(s): Philip Kocienski, Stewart Eccles
I. J. Krauss, M. Mandal, S. J. Danishefsky*
Sloan-Kettering Institute for Cancer Research and Columbia University, New York; Schering Plough Research Institute, Kenilworth, USA
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Publication History

Publication Date:
22 November 2007 (online)

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Significance

This paper describes the first total synthesis of isomigrastatin. Isomigrastatin is of ­interest because of its potential as a cancer cell migration suppressant.