Diverse FSH and Testosterone Signaling Pathways in the Sertoli Cell

E. S. Loss; A. P. Jacobus; G. F. Wassermann

doi:10.1055/s-2007-991167

Hormone and Metabolic Research, Inhaltsverzeichnis

Horm Metab Res 2007; 39(11): 806-812
DOI: 10.1055/s-2007-991167

Original Basic

Diverse FSH and Testosterone Signaling Pathways in the Sertoli Cell

E. S. Loss¹ , A. P. Jacobus¹ ^, ² , G. F. Wassermann¹

¹Departamento de Fisiologia, ICBS, UFRGS, Porto Alegre, RS, Brazil
²Centro Universitário Metodista IPA, Porto Alegre, RS, Brazil

Abstract

FSH and testosterone exert different regulatory effects on the seminiferous epithelium; they act through multiple and complex signaling routes to direct the development of the germ cells into mature spermatozoa. In addition to their well-known pathways of action, both hormones have recently been recognized to have new signaling routes that are linked to the Ca²⁺ ion, including, among others, the regulation of cell proliferation by FSH and the regulation of cell migration by testosterone.

Key words

FSH - testosterone - Sertoli cell - Ca²⁺ - rapid signaling

Volltext

Referenzen

References

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Correspondence

G. F. Wassermann

Departamento de Fisiologia

ICBS

UFRGS

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Porto Alegre

Rio Grande do Sul

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Brazil

Telefon: +55/51/3308 33 02

Fax: +55/51/3308 33 02

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