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DOI: 10.1055/s-2007-987191
Securidacaxanthones B and C, xanthones from Securidaca longepedunculata (Polygalaceae)
New compounds 1,5-dihydroxy-3,4,6,7,8-pentomethoxyxanthone (1) and 5-O-prenyl-1-hydroxy-,3,4,6,7,8-pentamethoxyxanthone (2), together with seven known compounds: 2-hydroxy-1,7-dimethoxyxanthone (3), 1,7-dihydroxyxanthone, 1,7-dihydroxy-4-methoxyxathanthone, β-sitosterol, 3-O-β-D-glucopyranosyl-β-sitosterol, quercetin-3-O-β-galactopyranoside and 3-hydroxy-6-methoxysalicylic acid, were isolated from the ethyl acetate fraction of the root part (whole root) of Securidaca longepedunculata Fresen. The structures of these compounds were established by means of spectroscopic (NMR) methods. Some of the isolated xanthones showed moderate antimicrobial activity.
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Acknowledgements: CQM is funded by Fundação para a Ciência e Tecnologia (FCT) and FEDER. This work had financial support from programme INTERREG, project BIOPOLIS. A. Meli Lannang, is thankful to the TWAS for financial support for research and advanced training at the H.E.J Research Institute of Chemistry, International Center of Chemical Sciences, Pakistan.
References: [1] Meli AL, Lontsi D, Ngounou FN, Sondengam BL, Nkengfack AE, Heerden FR, Assob JCN, (2006) Fitoterapia 77: 199–202.