Semin Respir Crit Care Med 2007; 28(4): 441-450
DOI: 10.1055/s-2007-985665
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Pulmonary Manifestations of Systemic Lupus Erythematosus

Beatrice Memet1 , Ellen M. Ginzler1 , 2
  • 1Division of Rheumatology, State University of New York-Downstate Medical Center, Brooklyn, New York
  • 2Department of Medicine, State University of New York-Downstate Medical Center, Brooklyn, New York
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Publikationsverlauf

Publikationsdatum:
03. September 2007 (online)

ABSTRACT

Systemic lupus erythematosus (SLE) can affect the lung in multiple ways. All components of the respiratory system, including the pleura, pulmonary parenchyma, airways, vessels, and respiratory muscles can be involved in various degrees at some time in the disease course and contribute to its morbidity and mortality. This article reviews the clinical symptoms, imaging techniques, histopathology, prognosis, and treatment of pulmonary manifestations of SLE and the related disorder mixed connective tissue disease (MCTD), from a historical perspective and with regard to new insights into pathogenesis and therapy.

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Ellen M GinzlerM.D. 

State University of New York-Downstate Medical Center

450 Clarkson Ave., Box 42, Brooklyn, NY 11203

eMail: ellen.ginzler@downstate.edu