Genexpression bei entzündlich-rheumatischen Erkrankungen

Schlüsselwörter

Monozyten - rheumatoide Arthritis - ankylosierende Spondylitis - systemischer Lupus erythematodes - Entzündung - Genexpressionsanalysen

Key words

monocytes - rheumatoid arthritis - ankylosing spondylitis - systemic lupus erythematodes - inflammation - gene expression profiling

Literatur

• 1 Baechler E C, Batliwalla F M, Karypis G, Gaffney P M, Ortmann W A, Espe K J. et al . Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.  Proc Natl Acad Sci U S A. 2003;  100 2610-2615
• 2 Batliwalla F M, Baechler E C, Xiao X, Li W, Balasubramanian S, Khalili H. et al . Peripheral blood gene expression profiling in rheumatoid arthritis.  Genes Immun. 2005;  6 388-397
• 3 Burmester G R, Stuhlmuller B, Keyszer G, Kinne R W. Mononuclear phagocytes and rheumatoid synovitis. Mastermind or workhorse in arthritis?.  Arthritis Rheum. 1997;  40 5-18
• 4 Häupl T, Grützkau A, Grün J, Radbruch A, Burmester G -R. Expression analysis of rheumatic diseases, prospects and problems. Progress in Inflammation Research In: The Hereditary Basis of Rheumatic Diseases, Editor Holmdahl 2006
• 5 Häupl T, Krenn V, Stuhlmuller B, Radbruch A, Burmester G R. Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies.  Arthritis Res Ther. 2004;  6 140-146
• 6 Lindberg J, af K lint E, Catrina A I, Nilsson P, Klareskog L, Ulfgren A K, Lundeberg J. Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients.  Arthritis Res Ther. 2006;  8 R179
• 7 Olsen N, Sokka T, Seehorn C L, Kraft B, Maas K, Moore J. et al . A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells.  Ann Rheum Dis. 2004;  63 1387-1392
• 8 Szaniszlo P, Wang N, Sinha M, Reece L M, Van Hook J W, Luxon B A. et al . Getting the right cells to the array: Gene expression microarray analysis of cell mixtures and sorted cells.  Cytometry A. 2004;  59 191-202