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Synthesis 2007(14): 2149-2152
DOI: 10.1055/s-2007-983730
DOI: 10.1055/s-2007-983730
PAPER
© Georg Thieme Verlag Stuttgart · New York
Efficient Synthesis of 2-Substituted 7-Azaindole Derivatives via Palladium-Catalyzed Coupling and C-N Cyclization Using 18-Crown-6
Further Information
Received
26 April 2007
Publication Date:
18 June 2007 (online)
Publication History
Publication Date:
18 June 2007 (online)
![](https://www.thieme-connect.de/media/synthesis/200714/lookinside/thumbnails/10.1055-s-2007-983730-1.jpg)
Abstract
A practical and straightforward preparation of various novel 2-substituted 7-azaindole derivatives from 2-amino-3-iodopyridine by a two-step procedure is described that gives the desired compounds in good overall yields.
Key words
alkynes - 7-azaindoles - 18-crown-6 - heterocycles - palladium catalysis
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