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Horm Metab Res 1995; 27(4): 182-184
DOI: 10.1055/s-2007-979935
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© Georg Thieme Verlag Stuttgart · New York

Estrogen Dependent LDH-Y, a New LDH Isozyme and Fertility Factor in Mice Uterus during Early Pregnancy

P. P. Singh3 , V. N. Singh1 , S. K. Sirmour2
  • 1University Department of Zoology, Bhagalpur University, Bhagalpur, India
  • 2Biosciences Research Centre, T.N.B. College Bhagalpur, India
  • 3Mahadeo Singh College, Bhagalpur, India
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Publication History

1994

1994

Publication Date:
23 April 2007 (online)

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Abstract

In estrogen treated ovariectomized and pregnant mice on the first day after mating a sixth LDH isozyme appeared at Relative mobility (Rm) 0.08 to 0.15 and for convenience this isozyme is provisionally designated as LDH-Y. The appearance of a sixth LDH isozyme (LDH-Y) in mice uterus after ovariectomy and estrogen treatment favours the idea that this isozyme is estrogen dependent. Presence of this LDH-Y in mice uterus during preimplantation and finally its sudden disappearance during implantation and post implantation periods further suggest that LDH-Y is estrogen dependent and responsible for restoring fertility in mice.

Key words

LDH-Y Isozyme - Estrogen and Fertility