Horm Metab Res 1998; 30(3): 153-157
DOI: 10.1055/s-2007-978856
Originals Clinical

© Georg Thieme Verlag Stuttgart · New York

Insulin Resistance, Dehydroepiandrosterone Sulfate and Sex Hormone-Binding Globulin in Essential Hypertension*

J. Serrano-Gotarredona1 , H. F. Escobar-Morreale2 , J. M. Sancho2 , R. García-Robles2
  • 1Department of Endocrinology. Hospital General Universitario de Alicante, Spain
  • 2Department of Endocrinology, Hospital Ramón y Cajal, Madrid, Spain
* Presented in part at the 7th European Meeting on Hypertension, Milán, Italy, June 1995
Further Information

Publication History

1997

1997

Publication Date:
20 April 2007 (online)

Objective: To evaluate insulin sensitivity, and serum levels of sex hormone-binding globulin (SHBG) and dehydroepiandrosterone sulfate (DHEA-sulfate), in patients with essential hypertension. Design and methods: In 15 non-treated hypertensive patients, insulin resistance was measured by an insulin suppression test (IST). Serum levels of DHEA-sulfate and SHBG were measured at the beginning and at the end of the IST. The results were compared to those of a control group of 10 healthy normotensive subjects matched for age, sex and body mass index (BMI).