Neuropediatrics 1998; 29(5): 249-254
DOI: 10.1055/s-2007-973570
Original articles

© Hippokrates Verlag GmbH Stuttgart

Partial Seizures Associated with Antiphospholipid Antibodies in Childhood

Lucia Angelini1 , T. Granata1 , F. Zibordi1 , S. Binelli2 , C. Zorzi1 , C. Besana3
  • 1Departments of Neuropediatrics National Neurological Institute "C. Besta", Milano, Italy,
  • 2Departments of Neurophysiology, National Neurological Institute "C. Besta", Milano, Italy,
  • 32nd Department of Internal Medicine, University of Milano, IRCCS San Raffaele, Milano, Italy
Further Information

Publication History

Publication Date:
12 March 2007 (online)

Abstract

We report antiphospholipid antibody positivity in three of a consecutive series of 23 children presenting partial epileptic seizures. There was no clinical or serological evidence of systemic lupus erythematosus or other connective-tissue disease.

Neither computed tomography nor magnetic resonance imaging revealed ischemic alteration. The presence of antiphospholipid antibodies in 3/23 children may indicate that immune-mediated neuronal damage could be a pathogenetic mechanism for partial epilepsy.