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Planta Med 1981; 43(10): 194-201
DOI: 10.1055/s-2007-971499
Research Articles

© Hippokrates Verlag Stuttgart

Studies on Scutellariae Radix

Part II: The Antibacterial Substance1 M. Kubo2 , Y. Kimura3 , T. Odani2 , T. Tani3 , K. Namba3
  • 2Faculty of Pharmaceutical Science, Kinki University, Higashiosaka, Osaka, Japan
  • 3The Research Institute of Oriental Medicine, Kinki University, Minami-kawachi-gun, Osaka, Japan
1 Part I: KUBO, M., Kimura, Y., Kosoto, H., Tani, T., Arichi, S., J. Histor. Pharm., submitted.
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Publication Date:
30 March 2007 (online)

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Abstract

Ogon, an important Chinese crude drug (the dried roots of Scutellaria baicalensis GEORGI), is listed in ancient Chinese herbals and is used in the treatment of a number of diseases. Ether extract of this crude drug showed a relatively marked antibacterial activity against Gram-positive bacteria. Fractionation of the extract accompanied by the bioassay led to the isolation of active principles. The structure of one of these was elucidated as 2(S), 2′, 5, 6′, 7-tetrahydroxyflavanone.

Key Word Index

Scutellaria baicalensis - Labiatae - Flavone - Flavanone - Antibacterial activity - 2(S), 2′,5,6′,7-tetrahydroxy flavanone