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Planta Med 1981; 43(10): 153-160
DOI: 10.1055/s-2007-971492
DOI: 10.1055/s-2007-971492
Research Articles
© Hippokrates Verlag Stuttgart
Transformation of Alkaloids of the Colchicine Type in Leaves and Flowers of Colchicum autumnale and C. byzantinum
A Simplified Isolation Procedure1,2 1 This paper constitutes Pan LXXXVIII on Isolation and Chemistry of Alkaloids from Plants of the Subfamily Wurmbaeoideae. Part LXXXVII: Acta Univ. Olomuc., Fac. Med. (Olomouc) 99, 115(1981).2 Dedicated to the Sixtieth Birthday of Prof. Dr. H. Oelschläger, Frankfurt a./MainWeitere Informationen
Publikationsverlauf
Publikationsdatum:
30. März 2007 (online)
Abstract
It was found that the so far described variations in the content of colchicine alkaloids in leaves and flowers of Colchicum autumnale L. and C. byzantinum Ten. are due to enzymatic O-demethylation and degradation of colchicine (I), N-deacetyl-N-formylcolchicine (XI), and demecolcine (XVII) during drying and storing of the plant material. A simplified method was elaborated to separate the neutral, phenolic, basic, and basic-phenolic fractions of tropolone alkaloids.
Key Word Index
Colchicum autumnale - Colchicum byzantinum - Liliaceae - Colchicine Alkaloids - Enzymatic Degradation - Simplified Separation