Vascular Microanastomosis in Rat Femoral Arteries: Experimental Study Comparing Non-Absorbable and Absorbable Sutures

ABSTRACT

Microsurgery is the procedure of choice for vascular anastamoses between 0.5 and 0.8 mm in diameter. The objective of this study was to compare two types of suture materials: non-absorbable, commonly used for vascular anastamoses in microsurgery, vs absorbable, rarely evaluated in this type of surgery. Twenty albino Wistar rats (average weight: 220 g) were operated on under the surgical microscope with an enlargement from X3.2 to X20, to perform a transvers section of both femoral arteries immediately followed by an anastamosis. The interventions were performed under general anaesthesia with an intramuscular injection associating ketamine with chlorpromazine. The animals were randomly placed into two groups of ten.

The reported results from macroscopic, histologic, and functional evaluations revealed no significant differences between the two types of sutures. However, local giant-cell inflammatory reaction was more important with the non-absorabable suture. This result should be further explored in studies using absorbable sutures in human microsurgery.

KEYWORDS

Vascular anastamosis - absorbable suture - microsurgery

REFERENCES

• 1 Serafin D. Microsurgery: past, present and future.  Plast Reconstr Surg. 1980;  66 781-785
• 2 Germain M A, Legagneux J. Vascular microsurgery and progress of free flap surgery.  Ann Chir. 2001;  126 960-968
• 3 Dahlke H, Dociu N, Thurau K. Synthetic resorbable and synthetic non-absorbable suture materials in microvascular surgery. Animal experimental study.  Handchirurgie. 1979;  11 3-13
• 4 Huang G K, Li H Q, Wu X M. Study on microvascular anastomosis of arteries with absorbable polyglyconate suture.  Microsurgery. 1995;  16 505-509
• 5 Chow S P, Huang C D, Chan C W. Microvascular anastomosis of arteries under tension.  Br J Plast Surg. 1982;  35 82-87
• 6 Daniel R K, Olding M. An absorbable anastomotic device for microvascular surgery: clinical applications.  Plast Reconstr Surg. 1984;  74 329-336
• 7 Sheynkin Y R, Lip S, Magid M L, Carlson D, Chen E C, Goldstein M. Comparison of absorbable and nonabsorbable sutures for microsurgical vasovasostomy in rats.  Urology. 1999;  53 1235-1238
• 8 Banic A, Francis I, Nilsson U. A comparative study of the use of 9-0 PDS and 9-0 prolene in microvascular anastomosis.  J Reconstr Microsurg. 1990;  6 293-297
• 9 Fried M P, Caminear D S, Sloman-Moll E R. The efficacy of absorbable suture for microvascular anastomoses.  Arch Otolaryngol Head Neck Surg. 1990;  116 1051-1054
• 10 Takeishi M, Hirase Y, Kojima T. Microsurgical use of polydioxanone (PDS) suture: an experimental report.  Microsurgery. 1992;  13 268-272
• 11 Chiu I S, Hung C R, Chao S F, Huang S H, How S W. Growth of the aortic anastomosis in pigs. Comparison of continuous absorbable suture with nonabsorbable suture.  J Thorac Cardiovasc Surg. 1988;  95 112-118