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Planta Med 1983; 49(12): 211-215
DOI: 10.1055/s-2007-969853
Research Articles

© Hippokrates Verlag Stuttgart

Gentiogenal, a Conversion Product of Gentiopicrin (Gentiopicroside)*

W. G. van der Sluis1 , J. M. van der Nat1 , A. L. Spek2 , Y. Ikeshiro3 , R. P. Labadie1
  • 1Farmaceutisch Laboratorium, sectie Farmacognosie Rijksuniversiteit Utrecht, The Netherlands
  • 2Laboratorium voor Structuurchemie Rijksuniversiteit Utrecht, The Netherlands
  • 3Niigata College of Pharmacy, Japan
* Part VI in the series: “Secoiridoids and Xanthones in the genus Centaurium”, for part V see ref. 5. Parts of these studies were presented at the 30th annual meeting of the Gesellschaft für Arzneipflanzenforschung in Graz, Austria, Juli 12-17, 1982, for summary see ref. 18.
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1983

1983

Publication Date:
26 March 2007 (online)

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Abstract

The structure of gentiogenal, (±)5-formyl-6-methyl-3,4-dihydro-1H,6H-pyrano-[3,4-c-]-pyran-1-one, a conversion product of the aglucone of gentiopicrin (gentiopicroside), isolated from Blackstonia perfoliata (Gentianaceae), was elucidated by 1H- and 13C NMR spectroscopic, mass spectrometric and X-ray diffraction methods.

In a TLC bioassay gentiogenal showed fungitoxicity towards Penicillium expansum.

Key Word Index

Blackstonia perfoliata - Gentianaceae - Gentiogenal - Gentiopicrin aglucone - Gentiopicrin - Gentiopicroside - Secoiridoids - Isolation - Structure elucidation